Immunomodulatory effects of selenium and vitamin E on alterations in T lymphocyte subsets induced by T-2 toxin.

Unlabelled: Abstract Context: T-2 toxin, a potent mycotoxin, has serious effects on immune system.

Objective: Here, the effects of a sublethal dose of this toxin on T lymphocyte sub-population levels and the potential protective effects from treatment with selenium or vitamin E were studied.

Materials And Methods: After having determined the sublethal dose of the T-2 toxin in Balb/c mice hosts, the post-injection kinetics of changes in T lymphocyte sub-population (CD3(+), CD4(+) and CD8(+) cells) profiles were analyzed via flow cytometry.