Topographical and Ultrastructural Evaluation of Titanium Plates Coated with PLGA, Chitosan, and/or Meropenem: An In Vitro Study.

The present investigation was undertaken to evaluate the topographical and ultrastructural architecture of titanium plates coated with polylactic co-glycolic acid (PLGA), chitosan (CH), and/or meropenem (MEM) with or without () or () bacteria. Single-hole segments of 0.4 mm thick, low-profile titanium plates were spray coated using an airbrush with polymeric carriers (PLGA or CH) loaded with MEM, in addition to the negative control group (uncoated titanium plates).

Microbiological Assessment of Titanium Plates Coated with PLGA, Chitosan, and/or Meropenem: An In Vitro Study.

This investigation was conducted to evaluate the efficacy of coated titanium plates against gram-positive and gram-negative using various methods. The Colony-forming unit "CFU" was higher in chitosan (CH) in relation to than in poly lactic-co-glycolic acid (PLGA) in relation to , followed by meropenem-chitosan "MC" coated plates in relation to and . A significant difference in the zone of inhibition (ZOI) of was determined in MP, MC, and meropenem (MEM).