Comparison of the antisclerotic effect of hydroalcoholic extracts of and with quinacrine by inhibition of phospholipase A in male Wistar rats.

Objective: Hypercholesterolemia is now considered a major risk factor for development of atherosclerosis. The phospholipase A2 superfamily of enzymes has causal involvement in atherosclerosis. Atherosclerosis is one of the main causes of mortality in developed countries and in some developing countries such as Iran.