Protective role of hypothermia on ischemia of prepubertal rodent testicle.

Objectives: To assess the role of hypothermia in testicular ischemic injury in a prepubertal rat model.

Methods: The study included 24 male, prepubertal Sprague-Dawley rats. Of the 24 rats, 20 were subjected to right testicular ischemia with and without hypothermia for 30 and 60 minutes, 5 in each group.

Factors affecting outcome of tubularized incised plate (TIP) urethroplasty: single-center experience with 500 cases.

Purpose: To review our experience of tubularized incised plate (TIP) urethroplasty in children with hypospadias defects.

Methods: Of 500 children (mean age 6 years) who received a TIP urethroplasty, 439 (87.8%) had primary hypospadias and 61 had one failed previous repair.

Chemotherapy as monotherapy for treatment of non-metastatic bladder/prostate embryonal rhabdomyosarcoma in children: preliminary report.

Objective: This work aims at evaluation of chemotherapy as mono-therapy for treatment of non-metastatic bladder/prostate embryonal rhabdomyosarcoma in children.

Patients And Methods: Between 1996 and 2002, 10 children presented with RMS of the bladder/prostate at a mean age of 6.6 years (range 1.

Surgical management of failed pyeloplasty in children: single-center experience.

Purpose: To evaluate the outcome of secondary surgical procedures for the management of failed pyeloplasty in children.

Materials And Methods: Between 1996 and 2007, 590 cases of primary ureteropelvic junction (UPJ) obstruction underwent open dismembered pyeloplasty at our center. Of these patients, 18 (3%) with recurrent UPJ obstruction (14 males, 4 females; age range: 2-15 years) have undergone management of failed pyeloplasty.

Urofacial syndrome.

The urofacial or Ochoa syndrome is a rare disease. We report on 2 patients of middle-eastern origin, with a review of the current literature to further document the existence of this syndrome, and to increase the general awareness of the classical facial characteristics, which facilitates diagnosis.

Complete primary repair of bladder exstrophy in children presenting late and those with failed initial closure: single center experience.

Purpose: Complete primary repair (CPR) of bladder exstrophy using Mitchell's technique gained wide popularity. We present a single center experience with CPR in 30 children with bladder exstrophy presenting late or after failed initial closure.

Materials And Methods: Between November 1998 and November 2003, 45 patients underwent CPR of bladder exstrophy using Mitchell's technique.

Postnatal unilateral pelviureteral junction obstruction: impact of pyeloplasty and conservative management on renal function.

Objectives: To study the effect of pyeloplasty and conservative management on renal function in children with pelviureteral junction obstruction.

Methods: This prospective study included 65 children postnatally diagnosed with unilateral pelviureteral junction obstruction. On the basis of the patients' symptoms and technetium-99m diethylenetriamine pentaacetic acid renal isotope scan findings, symptomatic patients or those with split function of the corresponding kidney of 40% or less were assigned to group 1 (n = 35) and underwent pyeloplasty.

Complete repair of bladder exstrophy in boys: can hypospadias be avoided?

Introduction: Complete repair of classic bladder exstrophy in male newborns has been successful with minimal morbidity. However, the technique may create hypospadias in some cases. We have recently adopted a modification to obtain an orthotopic meatus in bladder exstrophy boys.

Complete repair of bladder exstrophy: management of resultant hypospadias.

Purpose: In our hands complete primary repair (CPR) of bladder exstrophy results in hypospadias in two-thirds of boys. To our knowledge hypospadias repair following CPR of bladder exstrophy has not been reported previously. We report our experience with hypospadias repair following CPR of bladder exstrophy.

Percutaneous nephrolithotomy in children: early and late anatomical and functional results.

Purpose: We report our experience with percutaneous nephrolithotomy (PCNL) in children, and evaluate its early and late anatomical and functional results.

Materials And Methods: A total of 65 children with renal calculi were treated with PCNL. Patient age at operation ranged from 9 months to 16 years (mean +/- SD of 5.

Use of single layer small intestinal submucosa for long segment ureteral replacement: a pilot study.

Purpose: Previous studies have demonstrated successful use of small intestinal submucosa (SIS) as a tube for replacing short segment (11 mm) proximal ureteral defects. However, such small segment ureteral defects could be managed by resection re-anastomosis. We evaluated the use of 1-layer SIS as a tube for the replacement of long segment ureteral defects.

Complete repair of exstrophy: further experience with neonates and children after failed initial closure.

Purpose: The surgical repair of bladder exstrophy remains challenging for the urologist. Recently, complete primary repair has been used in neonates. We present our experience with this approach in neonates and children after failed initial closure.