Elaboration of chitosan nanoparticles loaded with star anise extract as a therapeutic system for lung cancer: Physicochemical and biological evaluation.

The research study aimed to maximize the important medical role of star anise extract (SAE) through its loading on a widely available natural polymer (chitosan, Cs). Thus, SAE loaded chitosan nanoparticles (CsNPs) was prepared. The finding illustrated the formation of spherical particles of SAE loaded CsNPs as proved by transmission electron microscope (TEM).

Very long versus overlapping drug eluting stents for the management of long coronary artery lesions.

Background: The prevalence of long diffuse coronary artery disease (CAD) is increasing nowadays due to increase prevalence of multiple risk factors and population ageing. We aimed in our study to show the differences clinically or angiographically (guided by IVUS) between the use of single long stent versus overlapping stents in very long coronary lesions (≥40 mm) in patients presented with chronic coronary syndromes.

Methods: 550 patients presenting with chronic coronary syndromes were included: 320 treated with a single long stent (≥40 mm) and 230 patients with two or more overlapping stents.

Egyptian Society of Liver Cancer Recommendation Guidelines for the Management of Hepatocellular Carcinoma.

Globally, hepatocellular carcinoma (HCC) is the fourth most common cause of death from cancer. The prevalence of this pathology, which has been on the rise in the last 30 years, has been predicted to continue increasing. HCC is the most common cause of cancer-related morbidity and mortality in Egypt and is also the most common cancer in males.

Comparative Study Between the Efficacy of Fractional CO Laser/Radiofrequency, PRP and a Combination of Both in the Treatment of Striae Distensae: A Pilot Study.

Purpose: The work aims to compare the effect of platelet-rich plasma versus fractional CO2 laser/radiofrequency versus both methods combined in treating striae distensae.

Patients & Methods: The study included ten female patients with striae alba with Fitzpatrick IV skin. Three sites of striae were chosen; one was treated with platelet-rich plasma, another with fractional CO /radiofrequency (CO/RF), and the third received both treatments.

Adsorption Study of Congo Red Dye from Synthetic Wastewater at Different Concentrations Using Zinc Sulfide Nanoparticles.

Zinc sulfide (ZnS) nanoparticles were fabricated using the chemical precipitation method. The X-ray diffraction (XRD), Raman spectroscopy, and scanning electron microscopy (SEM) techniques were used to investigate the structural parameters of the formed ZnS. The hexagonal crystal structure of the Zn and ZnS phases was formed.

Clinical evaluation of circulating miR-548a-3p and -20a expression in malignant pleural mesothelioma patients.

Aim: miRNAs may act as promising diagnostic and prognostic biomarkers of mesothelioma. This study integrates serum  miR-548a-3p and miR-20a expression based on in silico data analysis followed by clinical validation in malignant mesothelioma patients (malignant pleural mesothelioma [MPM]).

Patients & Methods: Serum miR-548a-3p and  miR-20a level was assessed in the serum of patients with MPM, chronic asbestos exposure and healthy volunteers by quantitative real-time PCR.