High Prevalence of GES-5 Variant and Co-Expression of VIM-2 and GES-45 among Clinical Strains in Tunisia.

Carbapenem-resistant (CRPA) are a global health concern. The antimicrobial resistance, virulence, and molecular typing of 57 CRPA isolated from 43 patients who attended a specific Tunisian hospital from September 2018 to July 2019 were analyzed. All but one were multidrug-resistant CRPA, and 77% were difficult-to-treat-resistant (DTR) isolates.

Serotype Occurrence, Virulence Profiles, Antimicrobial Resistance and Molecular Characterization of Isolated from Hospitalized Patients with Gastroenteritis in Great Tunisia between 2010 and 2020.

Non-typhoid is one of the major causes of food-borne infections worldwide. The aim of the current study is to determine the serotype occurrence, virulence factors and antimicrobial resistance patterns of isolated from hospitalized patients. The identification of strains was performed according to REMIC, 2018.

Efficiency of a Tetracycline-Adjuvant Combination Against Multidrug Resistant Tunisian Clinical Isolates.

The growing number of multidrug resistant strains in Tunisia has become a serious health concern contributing to high rate of mortality and morbidity. Since current antibiotics are rapidly becoming ineffective, novel strategies to combat resistance are needed. Recently, we demonstrated that combination of a tetracycline antibiotic with various polyaminoisoprenyl adjuvants can sustain the life span and enhance the activity of these drugs against reference strain (PA01).

First Report of NDM and VIM Coproducing in Tunisia and Emergence of Novel Clones.

Metallo-β-lactamase (MBL) producing bacteria constitute nowadays a serious global concern worldwide. The purpose of our present study was to characterize molecular features of MBL producing bacteria and to identify the existing clones in our area. Thirteen MBL-producing- were detected in clinical samples from patients hospitalized in the Military hospital of Tunisia during 2017.

Huge Diversity of TEM and SHV β-Lactamases Types Among CTX-M-15-Producing Enterobacteriaceae Species in Tunisia.

The aim of our study was to characterize third-generation cephalosporin (3GC)-resistant Enterobacteriaceae isolated over two different periods from patients hospitalized in the Military Hospital of Tunis with special focus to class A β-lactamases. This study included 180 Enterobacteriaceae resistant to 3GC isolated from samples of patients hospitalized in various services of the hospital. Enterobacteriaceae species detected by the Vitek 2 Compact (BioMérieux) automated system showed the dominance of followed by during both periods.

Screening for Carbapenemases in Ertapenem-Resistant Collected at a Tunisian Hospital Between 2014 and 2018.

Background: Carbapenem-resistance is frequently detected in isolated from patients in Tunisia. The study was performed to identify frequent carbapenemases in Tunisian isolates.

Methods: Between May 2014 and January 2018, 197 ertapenem-resistant were isolated at the microbiological department of the Military Hospital of Tunis.

Vancomycin-Resistant in Tunisia: Emergence of Novel Clones.

Vancomycin-resistant Enterococci (VRE) are a major public health problem worldwide, since they are commonly implicated in nosocomial infections in various regions in the world. The aim of our study was to investigate genetic features and clonal relationship of VRE in the Military hospital of Tunisia. A total of 10 VRE strains were initially detected and identified by the Viteck II compact (BioMérieux) automated system, then confirmed by PCR using specific primers.

Occurrence and Characterization of Carbapenemase-Producing Enterobacteriaceae in a Tunisian Hospital.

Carbapenem-resistant Enterobacteriaceae have become of particular concern, since they were quickly disseminated in various areas in the world. The aim of the study was to investigate the prevalence of carbapenemase production among clinical isolates of Enterobacteriaceae recovered from the Military Hospital of Tunisia. Bacterial isolates (n = 125) were recovered from patients in diverse services from March 2014 to February 2016 and identified by Vitek II Compact.