A postal survey of hereditary hemorrhagic telangectasia in the northeast of England.

The aim of this study is to identify the demographics and epistaxis burden of hereditary hemorrhagic telangiectasia (HHT). A questionnaire was sent to participants with HHT who were recruited from a prospectively maintained respiratory clinic data base in a tertiary hospital. Details on demographics, HHT symptoms, family history, epistaxis severity, and treatment received were recorded.

Efficacy of a marine bacterial nuclease against biofilm forming microorganisms isolated from chronic rhinosinusitis.

Background: The persistent colonization of paranasal sinus mucosa by microbial biofilms is a major factor in the pathogenesis of chronic rhinosinusitis (CRS). Control of microorganisms within biofilms is hampered by the presence of viscous extracellular polymers of host or microbial origin, including nucleic acids. The aim of this study was to investigate the role of extracellular DNA in biofilm formation by bacteria associated with CRS.

Accuracy of predissection assessment of the lower lateral cartilage configuration: a cadaveric study.

Background: Preoperative planning of nasal tip surgery requires an accurate assessment of the nasal tip cartilages configuration. The current literature lacks any evidence on the accuracy of preoperative assessment of the lower lateral cartilages (LLC) shape.

Objective: This study was designed to determine the accuracy of the LLC shape and configuration assessment prior to dissection.

Prospective study to assess vocal cord palsy investigations.

Objectives: To assess the investigation and clinical outcome of patients presenting with unexplained vocal cord palsy (VCP).

Study Design And Methods: A prospective cohort study designed to evaluate 86 patients with unexplained VCP presenting to our tertiary referral center.

Results: Twenty-four (36%) patients had positive findings on CT scanning.

Predictive value of sleep nasendoscopy in the management of habitual snorers.

Sleep nasendoscopy (SN) is claimed to identify the site of obstruction in habitual snoring and is used to select patients for palatal surgery. The validity of SN is, however, unproven. This is the first prospective blind assessment of the role of SN in the management of habitual snorers.