Lignites are widely available and cost-effective in many countries. Sustainable methods for their utilization drive innovation, potentially advancing environmental sustainability and resource efficiency. In the present study, FeO (∼25.
View Article and Find Full Text PDFWorld J Pediatr Congenit Heart Surg
July 2024
Truncus arteriosus is a rare congenital heart defect resulting from the failure of the truncus arteriosus to divide during fetal development. It leads to a single outflow tract from the heart and, if left untreated, can be fatal. Late presentation and repair can also increase the risk of pulmonary hypertensive crises, which can lead to morbidity and mortality after repair.
View Article and Find Full Text PDFExposure to bioaerosols has been associated with the occurrence of a variety of health impacts, including infectious illnesses, acute toxic effects, allergies, and cancer. This study aimed at evaluating airborne bacteria and fungi populations at different indoor and outdoor sites on a college campus in Bengaluru, India. Bioaerosol samples were collected using a two-stage Andersen air sampler; and isolates were identified using standard procedures.
View Article and Find Full Text PDFObjectives: To compare the outcome of coronary artery bypass grafting with and without cardiopulmonary bypassin patients of chronic obstructive pulmonary disease.
Method: The prospective randomised multicentre study was conducted in 2020 at Kafrelsheikh University Hospital, International Cardiac Centre and Alexandria New Medical Centre, Egypt. Patients regardless of age and gender who had ischaemic heart disease and chronic obstructive pulmonary disease were enrolled, and randomised into on-pump procedure group 1 and off-pump procedure group II.
Date fruit pomace (DFP), an abundant byproduct of the date syrup industry, is currently underutilized. It is either fed to animals or landfilled where it ferments, causing serious environmental issues. Proper waste management through valorization strategies is required to reduce the environmental impact of date waste and foster the transition of the date processing industry towards sustainability.
View Article and Find Full Text PDFQJM
May 2023
Background: Matricellular proteins comprising matrisome and adhesome are responsible for structure integrity and interactions between cells in the tumour microenvironment of breast cancer. Changes in the gene expression of matrisome and adhesome augment metastasis. Since inflammatory breast cancer (IBC) is characterized by high metastatic behaviour.
View Article and Find Full Text PDFInternational Management is a vast and multidisciplinary research domain that is heavily influenced by several other disciplines, such as Economics, Organizational Theory and Strategic Management. Based on 28,973 research articles, this study aims to analyze the knowledge structure of the international management domain from 1920 to 2019. Using computational text-based topic modeling analysis, we trace the evolution of international management knowledge by examining the major academic topics/latent themes discussed in the field.
View Article and Find Full Text PDFBiochim Biophys Acta Mol Cell Res
January 2023
Studies suggested that the pathogenesis of inflammatory breast cancer (IBC) is related to inflammatory manifestations accompanied by specific cellular and molecular mechanisms in the IBC tumor microenvironment (TME). IBC is characterized by significantly higher infiltration of tumor-associated macrophages (TAMs) that contribute to its metastatic process via secreting many cytokines such as TNF, IL-6, IL-8, and IL-10 that enhance invasion and angiogenesis. Thus, there is a need to first understand how IBC-TME modulates the polarization of TAMs to better understand the role of TAMs in IBC.
View Article and Find Full Text PDFSince its inception, YouTube has been a source of entertainment and education. Everyday millions of videos are uploaded to this platform. Researchers have been using YouTube as a source of information in their research.
View Article and Find Full Text PDFBackground: Inflammatory breast cancer (IBC) represents a deadly aggressive phenotype of breast cancer (BC) with a unique clinicopathological presentation and low survival rate. In fact, obesity represents an important risk factor for BC. Although several studies have identified different cellular-derived and molecular factors involved in IBC progression, the role of adipocytes remains unclear.
View Article and Find Full Text PDFInflammatory breast cancer (IBC) is a highly aggressive phenotype of breast cancer that is characterized by a high incidence early metastasis. We previously reported a significant association of human cytomegalovirus (HCMV) DNA in the carcinoma tissues of IBC patients but not in the adjacent normal tissues. HCMV-infected macrophages serve as "mobile vectors" for spreading and disseminating virus to different organs, and IBC cancer tissues are highly infiltrated by tumor-associated macrophages (TAMs) that enhance IBC progression and promote breast cancer stem cell (BCSC)-like properties.
View Article and Find Full Text PDFRestaurant research has received significant attention globally. This article aims to examine the evolution and the knowledge structure of restaurant research over the past decades. We also investigate the restaurant research hotspots and knowledge diffusion paths based on 1489 articles extracted from the Web of Science database.
View Article and Find Full Text PDFInflammatory breast cancer (IBC) is an aggressive phenotype with a high recurrence and low survival rate. Approximately 90% of local breast cancer recurrences occur adjacent to the same quadrant as the initial cancer, implying that tumor recurrence may be caused by residual cancer cells and/or quiescent cancer stem cells (CSCs) in the tumor. We hypothesized that wound fluid (WF) collected after modified radical mastectomy (MRM) may activate cancer cells and CSCs, promoting epithelial mesenchymal transition (EMT) and invasion.
View Article and Find Full Text PDFThis study utilizes bibliometric analyses to map and visualize the development, conceptual structure, and thematic evolution of the Islamic Banking and Finance (IB&F) scholarly research. It analyses 464 WoS IB&F research publications of 921 authors comprising 58 countries published over three decades from 1990 to 2019. The results reveal that (i) collaboration among countries is limited and institutional collaboration can be described as a "locally concentrated and globally isolated," (ii) the IB&F research is a type of "small-world-network" where few authors and journals dominate the networks and play a central role in the diffusion of knowledge and the "homophily impact" is present among the leading authors of the IB&F research, (iii) the networks in IB&F research reflects the "Matthew Effect," implying that few authors have a more significant number of networks compared to the rest of authors.
View Article and Find Full Text PDFFloods are among the devastating types of disasters in terms of human life, social and financial losses. Authoritative data from flood gauges are scarce in arid regions because of the specific type of dry climate that dysfunctions these measuring devices. Hence, social media data could be a useful tool in this case, where a wealth of information is available online.
View Article and Find Full Text PDFAutomated grading systems using deep convolution neural networks (DCNNs) have proven their capability and potential to distinguish between different breast cancer grades using digitized histopathological images. In digital breast pathology, it is vital to measure how confident a DCNN is in grading using a machine-confidence metric, especially with the presence of major computer vision challenging problems such as the high visual variability of the images. Such a quantitative metric can be employed not only to improve the robustness of automated systems, but also to assist medical professionals in identifying complex cases.
View Article and Find Full Text PDFBiochim Biophys Acta Mol Cell Res
May 2021
Locally advanced breast cancer (LABC) is an aggressive disease characterized by late clinical presentation, large tumor size, treatment resistance and low survival rate. Expression of EGFR/HER2 and activation of intracellular tyrosine kinase domains in LABC are associated with poor prognosis. Thus, target therapies such as the anti-receptor tyrosine kinases lapatinib drug have been more developed in the past decade.
View Article and Find Full Text PDFInflammatory breast cancer (IBC) is a highly metastatic and lethal breast cancer. As many as 25-30% of IBCs are triple negative (TN) and associated with low survival rates and poor prognosis. We found that the microenvironment of IBC is characterized by high infiltration of tumor associated macrophages (TAMs) and by over-expression of the cysteine protease cathepsin B (CTSB).
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
April 2020
This study was concerned with the temporal analysis of benzene, toluene, ethylbenzene, xylenes (BTEXs), and ozone in Rochester, New York, between 2012 and 2018. Additionally, the influence of ozone precursors (e.g.
View Article and Find Full Text PDFThe aim was to explore the impact of periconceptional folic acid or flaxseed oil (FXO) supplementation on fertility, progesterone profile, and blood chemistry in pregnant ewes during the breeding season. In total, 54 Ossimi ewes were divided into three groups (18 animals each). The control treatment (CON) fed a basal diet only, while the others fed the basal diet and supplemented every other day with a single bolus of folic acid (FO 500 μg/head) or flaxseed oil (FX 50 ml/head).
View Article and Find Full Text PDFHerein, we aimed to identify the immunomodulatory role of tumor Syndecan-1 (CD138) in the polarization of CD4+ T helper (Th) subsets isolated from the tumor microenvironment of inflammatory breast cancer (IBC) and non-IBC patients. Lymphocytes and mononuclear cells isolated from the axillary tributaries of non-IBC and IBC patients during modified radical mastectomy were either stimulated with the secretome as indirect co-culture or directly co-cultured with control and Syndecan-1-silenced SUM-149 IBC cells. In addition, peripheral blood mononuclear cells (PBMCs) of normal subjects were used for the direct co-culture.
View Article and Find Full Text PDFPurpose: Plasmacytoid dendritic cells (PDCs) infiltration into breast cancer tissues is associated with poor prognosis. Also, CXCR4 shows compelling evidences to be exploited by cancer cells to migrate to distant sites. The present study investigated lymph node metastasis in the light of PDCs infiltration and the potential cross talk with CXCR4/SDF-1 chemokine axis.
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