Essential Oil Biodiversity of All. Obtained from Mainland and Island Populations.

Background: The genus is rich in essential oil (EO) with high chemical diversity. In this study, eight EO samples obtained from flowers and leaves of All. collected on the Mediterranean mainland and island locations were analyzed to evaluate their possible chemical diversity.

Proapoptotic Activity of Essential Oil and Its Major Constituent 1,8-Cineole against A2780 Ovarian Cancer Cells.

Among the hundreds of reported species, (Labill.) DC. is one of the six that grow in Jordan.

Urease inhibitory potential of extracts and active phytochemicals of (Asteraceae).

Urease inhibition potential of compound (), guaiane-type sesquiterpene (), confertin () and scopoletin () was carried out with high throughout mechanism-based assay. These compounds were isolated from L., an Asteraceae family member.

In Vivo Study on Analgesic, Muscle-Relaxant, Sedative Activity of Extracts of and In Silico of Certain Compounds Present in This Species.

Background: (flatweed) from the family Asteraceae is a medicinal plant found in Europe, Middle East, and India. In folkloric medication, it is used to heal jaundice, dyspepsia, constipation, rheumatism, and hypoglycemia as well as renal problems. Leaves and roots of the plant have antioxidant and antibacterial properties.

Flavonoidal Constituents, Antioxidant, Antimicrobial, and Cytotoxic Activities of Grown in Kingdom of Saudi Arabia.

Background: Decne. herb is one of the common traditional plants with multiple medicinal uses.

Objective: To isolate the major constituents and to investigate the antioxidant, antimicrobial, and cytotoxic activities of this herb.

Formulation of Saudi Propolis into Biodegradable Chitosan Chips for Vital Pulpotomy.

Background: Propolis has been widely used to treat oral cavity disorders, such as endodontal and periodontal diseases and microbial infections.

Objective: The study aimed at the formulation of commercial Saudi propolis into biodegradable chitosan chips and evaluation of its effectiveness as a pulpotomy agent.

Methods: The standardization of 80% ethanolic propolis extract was performed regarding its total phenolic content, total flavonoid content, quantitative estimation of main polyphenolic constituents and antioxidant activity.

A New Sucrase Enzyme Inhibitor from Azadirachta indica.

Background: Sucrase enzyme inhibitor considered as an oral anti-diabetic therapy that delays the absorption of eaten carbohydrates, reducing the postprandial glucose and insulin peaks to reach normoglycemia.

Materials And Methods: Chromatographic fractionation of the hydroalcoholic extract of leaves of Azadirachta indica growing in KSA, followed by in-vitro assay of sucrase enzyme inhibition activity.

Results: This investigation led to the isolation of a new remarkable sucrase enzyme inhibitor; 4'-methyl Quercetin-7-O-β-D-glucuronopyranoside (1) alongside with four known compounds; 2,3-hexahydroxydiphenoyl-(α/β)-D-(4)C1-glucopyranose (2), Avicularin (3), Castalagin (4) and Quercetin-3-O-glucoside (5).

Bioassay-guided isolation and POM analyses of a new immunomodulatory polyphenolic constituent from Callistemon viridiflorus.

Chromatographic separation of 80% EtOH extract of Callistemon viridiflorus leaves led to the isolation of six known constituents (1-6) along with a new polyphenolic compound 7 identified as apigenin 4'-O-β-d-glucopyranosyl-(1″' → 4″)-O-β-d-glucopyranoside. The ethanolic extract of C. viridiflorus leaves and isolated compounds were evaluated for in vitro immunomodulatory activity by means of RAW 264.

Antioxidant and cytotoxic activity of polyphenolic compounds isolated from the leaves of Leucenia leucocephala.

Context: Cancer is a serious clinical problem to the health care system. Anticancer drugs have been extracted from plants containing phenolic compounds. Leucenia species (Fabaceae) contain a variety of bioactive components of numerous biological and pharmacological properties.

Homospermidine in transgenic tobacco results in considerably reduced spermidine levels but is not converted to pyrrolizidine alkaloid precursors.

Homospermidine synthase is the first specific enzyme in the biosynthesis of pyrrolizidine alkaloids. Whereas the substrates putrescine and spermidine are part of the highly dynamic polyamine pool of plants, the product homospermidine is incorporated exclusively into the necine base moiety of pyrrolizidine alkaloids. Recently, the gene encoding homospermidine synthase has been shown to have been recruited several times independently during angiosperm evolution by the duplication of the gene encoding deoxyhypusine synthase.