Publications by authors named "Mohamed Husien"

The characteristic of ulcerative colitis (UC) is extensive colonic mucosal inflammation. () is a medicine food homology plant, and the polysaccharide from leaves (MOLP) exhibits antioxidant and anti-inflammatory activity. The aim of this study to investigate the potential effect of MOLP on UC in a mouse model as well as the underlying mechanism.

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Article Synopsis
  • The PETCAM trial studied the impact of using PET-CT scans on the surgical management of patients with colorectal cancer liver metastases compared to no PET-CT scans.
  • The trial involved 404 patients and found no significant differences in long-term outcomes like disease-free survival (DFS) and overall survival (OS) between those who had PET-CT and those who didn't.
  • Ultimately, while PET-CT altered surgical decisions in 8% of cases, it did not influence recurrence rates or long-term survival after surgery.
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Background: Management of recurrence following liver resection for colorectal cancer metastases is a topic of debate. We determined risk factors for survival following recurrence after liver resection.

Methods: Long-term follow-up of patients in the PETCAM trial who had recurrence following liver resection.

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Importance: Patients with colorectal cancer with liver metastases undergo hepatic resection with curative intent. Positron emission tomography combined with computed tomography (PET-CT) could help avoid noncurative surgery by identifying patients with occult metastases.

Objectives: To determine the effect of preoperative PET-CT vs no PET-CT (control) on the surgical management of patients with resectable metastases and to investigate the effect of PET-CT on survival and the association between the standardized uptake value (ratio of tissue radioactivity to injected radioactivity adjusted by weight) and survival.

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