COVID-19 Severity Shifts the Cytokine Milieu Toward a Proinflammatory State in Egyptian Patients: A Cross-Sectional Study.

Despite extensive research to decipher the immunological basis of coronavirus disease (COVID-19), limited evidence on immunological correlates of COVID-19 severity from MENA region and Egypt was reported. In a single-center cross-sectional study, we have analyzed 25 cytokines that are related to immunopathologic lung injury, cytokine storm, and coagulopathy in plasma samples from 78 hospitalized Egyptian COVID-19 patients in Tanta University Quarantine Hospital and 21 healthy control volunteers between April 2020 and September 2020. The enrolled patients were divided into 4 categories based on disease severity, namely mild, moderate, severe, and critically ill.

Proposed Strategies to Improve Adult Asthma Management in Egypt: Expert Review and Recommendations.

Background: Several challenges face asthma management in Egypt, including the high percentage of uncontrolled patients, inadequate compliance, and overuse of short-acting beta-agonists (SABAs) leading to increased asthma-related morbidity and mortality. In this regard, the recent Global Initiative for Asthma (GINA) recommendations included inhaled corticosteroids containing therapy for mild asthma. Local healthcare systems and healthcare professionals (HCPs) often experience practical challenges when implementing global guidelines.

Trends in Dry Eye Disease Management Worldwide.

Dry eye disease (DED) is a condition frequently encountered in ophthalmology practice worldwide. The purpose of this literature review is to highlight the worldwide trends in DED diagnosis and therapy amongst practitioners and determine if a more uniform approach to manage this multifactorial condition has developed over the past two decades. A manual literature search utilizing PubMed was conducted to obtain papers with survey results relating to ophthalmology and optometry diagnosis and treatment of dry eye from January 2000 to January 2020.

Comparison of LASEK, mechanical microkeratome LASIK and Femtosecond LASIK in low and moderate myopia.

Purpose: We conducted a prospective study to determine the best treatment option for patients with low-to-moderate spherical myopia or myopic astigmatism who are considered equally eligible for LASEK with mitomycin-C (MMC) and LASIK with either mechanical microkeratome or femtosecond laser flap creation.

Methods: Forty-six adult patients (86 eyes) who underwent LASEK with MMC (16 patients, 31 eyes), and mechanical microkeratome LASIK (13 patients, 23 eyes) or Femtosecond LASIK (17 patients, 32 eyes) were assessed for clinical outcomes 1, 3 and 6 months post-operatively.

Results: Six months after surgery, all eyes in all three groups were within 1 D of the intended refractive change.

Efficacy and safety of Intacs SK in moderate to severe keratoconus.

Purpose: To examine the safety and efficacy of Intacs SK for moderate to severe keratoconus (KC) using femtosecond technology.

Materials And Methods: This prospective, non-comparative study included 37 contact lens intolerant keratoconic eyes (stage II-III) of 24 patients who underwent femtosecond-assisted Intacs SK implantation. Inclusion criteria were mean K readings <56.

Initial experience with Descemet stripping automated endothelial keratoplasty in Saudi Arabia.

Purpose: To analyze the visual results of Descemet stripping automated endothelial keratoplasty (DSAEK) in the first consecutive 10 cases.

Materials And Methods: Retrospective, non-randomized, non-comparative interventional case series. Ten eyes of 10 patients with endothelial dysfunctions of different etiology, scheduled for DSEAK, were included in this study.

Short-term visual outcomes of Boston keratoprosthesis type I in saudi arabia.

Purpose: To evaluate the visual outcomes, complications and retention of threadless type I Boston keratoprosthesis (KPro) in Saudi Arabia.

Materials And Methods: Retrospective analysis of four eyes of four patients (one female and three males; age range: 48 to 72 years) who underwent Boston type I threadless KPro implantation between January and December 2009.

Results: In the median follow-up of 11 months (range 6 to 14 months), visual outcomes were satisfactory.

Phototherapeutic keratectomy outcomes in superficial corneal opacities.

Purpose: COMPARE THE EFFECTIVENESS OF PHOTOTHERAPEUTIC KERATECTOMY (PTK) IN TREATMENT CORNEAL DYSTROPHIES VERSUS SUPERFICIAL CORNEAL SCARS: visual outcomes, recurrence rate and safety profile.

Methods: PTK was performed in 51 eyes of 51 patients. Data regarding the indications for PTK, ablation depth, symptomatic relief, pre-and postoperative best spectacle-corrected visual acuity (BSCVA), spherical equivalent changes, recurrence and complications were analyzed.

Initial experience with an accommodating intraocular lens: controlled prospective study.

Purpose: To evaluate the outcomes of implantation of an accommodating intraocular lens (IOL) in pseudophakic presbyopic eyes.

Setting: Ophthalmology Department, Benha Medical School, Benha, Egypt.

Methods: In this prospective controlled trial, near and distance visual acuities, the manifest refraction spherical equivalent, and patient satisfaction were evaluated in presbyopic eyes that had phacoemulsification cataract removal and implantation of a Crystalens AT-45 IOL accommodating IOL.

Comparison of postoperative wavefront aberrations after NIDEK CXIII optimized aspheric transition zone treatment and OPD-guided custom aspheric treatment.

Purpose: To compare higher order aberrations of aspheric or wavefront-guided myopic LASIK.

Methods: This was a prospective, randomized study of a myopic LASIK cohort that was subdivided into two groups; 12 eyes were treated with the optimized aspheric transition zone algorithm (OATz group) and 11 eyes were treated with wavefront-guided optimized path difference custom aspheric treatment (OPDCAT group). Corneal asphericity and higher order aberrations root-mean-square were compared between groups before, 1 month, and 3 months after LASIK.

Multizone LASIK with peripheral near zone for correction of presbyopia in myopic and hyperopic eyes: 1-year results.

Purpose: To investigate the refractive outcomes of multifocal LASIK to create a center far, peripheral near zone in presbyopes.

Methods: This prospective study using LASIK with a center far, peripheral near ablation algorithm comprised 68 eyes of 34 hyperopes and 78 eyes of 39 myopes. Mean patient age was 49 +/- 5.