Inhibition of microRNA-660-5p decreases breast cancer progression through direct targeting of TMEM41B.

Background: Breast cancer is the most prevalent cancer among women worldwide. Most breast cancer-related deaths result from metastasis and drug resistance. Novel therapies are imperative for targeting metastatic and drug-resistant breast cancer cells.

Cytotoxic and anti-diabetic potential, metabolic profiling and studies of (L.) Skeels belonging to family .

LC-HR-MS-coupled metabolic profiling of the methanol extracts from different parts of (L.), which was extensively identified DNA fingerprinting, led to dereplication of 24 compounds. Cytotoxic investigation highlighted both extracts as the most potent, against both MCF-7 and MDA-231 Cell lines, with IC value of 5.