Role of online hemodiafiltration in improvement of inflammatory status in pediatric patients with end-stage renal disease.

Introduction: Patients with end-stage renal disease are known to suffer from chronic inflammation as the result of an ongoing subacute cytokine induction, which may contribute considerably to dialysis-related long-term morbidity and mortality. In order to assess the inflammatory risk associated with online hemodiafiltration compared to conventional hemodialysis, we compared the cytokine induction profile of pediatric patients during treatment with each these modalities of dialysis.

Materials And Methods: Thirty pediatric patients on regular hemodialysis for at least 6 months were shifted to online hemodiafiltration.