Electrical excitability of roach ( Rutilus rutilus) ventricular myocytes: effects of extracellular K, temperature, and pacing frequency.

Exercise, capture, and handling stress in fish can elevate extracellular K concentration ([K]) with potential impact on heart function in a temperature- and frequency-dependent manner. To this end, the effects of [K] on the excitability of ventricular myocytes of winter-acclimatized roach ( Rutilus rutilus) (4 ± 0.5°C) were examined at different test temperatures and varying pacing rates.

Effects of seasonal acclimatization on thermal tolerance of inward currents in roach (Rutilus rutilus) cardiac myocytes.

To test the hypothesis of temperature-dependent deterioration of electrical excitability (TDEE) (Vornanen, J Exp Biol 219:1941-1952, 2016), the role of sodium (I ) and calcium (I ) currents in heat tolerance of cardiac excitability was examined in a eurythermic fish, the roach (Rutilus rutilus). Densities of cardiac I and I and their acute heat tolerance were measured in winter-acclimatized (WiR) and summer-acclimatized (SuR) fish maintained in the laboratory at 4 ± 1 and 18 ± 1 °C, respectively. A robust L-type Ca current (I ), but no T-type Ca current, was present in roach atrial and ventricular myocytes.

Clinical profile and outcomes of management of orbital cellulitis in Upper Egypt.

Background: The purpose of this paper is to study the etiology, clinical findings, and outcomes of management of cases of orbital cellulitis treated in Minia University Hospital in Upper Egypt over the period of 6 years from July 2009 to July 2015. One-hundred two patients diagnosed to have orbital cellulitis were admitted to the hospital and treated on inpatient basis from July 2009 to July 2015. All patients were subjected to full ophthalmological examination, systemic evaluation, and ear, nose, and throat (ENT) consultation.

Effects of seasonal acclimatization on action potentials and sarcolemmal K currents in roach (Rutilus rutilus) cardiac myocytes.

Temperature sensitivity of electrical excitability is a potential limiting factor for high temperature tolerance of ectotherms. The present study examines whether heat resistance of electrical excitability of cardiac myocytes is modified by seasonal thermal acclimatization in roach (Rutilus rutilus), a eurythermal teleost species. To this end, temperature dependencies of ventricular action potentials (APs), and atrial and ventricular K currents were measured from winter-acclimatized (WiR) and summer-acclimatized (SuR) roach.

Role of Avastin in management of central serous chorioretinopathy.

Purpose: To evaluate the short-term safety and efficacy of intravitreal bevacizumab for the treatment of intraretinal or subretinal fluid accumulation secondary to central serous chorioretinopathy (CSC).

Design: Prospective interventional series non-comparative study.

Setting: Department of Ophthalmology, Al-Minya University Faculty of Medicine, Egypt.

Serum anti-myelin-associated glycoprotein antibodies in Egyptian autistic children.

Autoimmunity to brain could play an etiopathogenic role in a subgroup of autistic patients. The frequency of serum anti-myelin-associated glycoprotein antibodies, as an index for autoimmunity to brain, and their relation to family history of autoimmunity were investigated in 32 autistic and 32 healthy matched children. Autistic children had significantly higher serum anti-myelin-associated glycoprotein antibodies than healthy children (2100 [1995] and 1138 [87.