Phosphonated Polyetheramine-Coated Superparamagnetic Iron Oxide Nanoparticles: Study on the Harsh Scale Inhibition Performance of Calcium Carbonate and Barium Sulfate.

Harsh scale buildup, such as calcium carbonate (calcite) and barium sulfate (barite), poses significant challenges in the oil and gas industry. While various scale inhibitors (SIs) are employed to mitigate this issue, there is a need for greener, more efficient, compatible, and affordable alternatives. Calcium compatibility often complicates the use of SIs, potentially leading to formation damage.

Black Titania Janus Mesoporous Nanomotor for Enhanced Tumor Penetration and Near-Infrared Light-Triggered Photodynamic Therapy.

Thanks to their excellent photoelectric characteristics to generate cytotoxic reactive oxygen species (ROS) under the light-activation process, TiO nanomaterials have shown significant potential in photodynamic therapy (PDT) for solid tumors. Nevertheless, the limited penetration depth of TiO-based photosensitizers and excitation sources (UV/visible light) for PDT remains a formidable challenge when confronted with complex tumor microenvironments (TMEs). Here, we present a HO-driven black TiO mesoporous nanomotor with near-infrared (NIR) light absorption capability and autonomous navigation ability, which effectively enhances solid tumor penetration in NIR light-triggered PDT.

Regiospecific Photochemical Synthesis of Methylchrysenes.

Methylated polycyclic aromatic hydrocarbons (PAHs) are suspected to be some of the toxic compounds in crude oil towards marine life and are needed as single compounds for environmental studies. 1-, 3- and 6-methylchrysene () were prepared as single isomers by photochemical cyclization of the corresponding stilbenoids in the Mallory reaction using stoichiometric amounts of iodine in 82-88% yield. 2-methylchrysene () was prepared by photochemical cyclization where the regioselectivity was controlled by elimination of an -methoxy group under acidic oxygen free conditions in 72% yield.

Green Synthesis, Characterization, Antimicrobial and Anticancer Screening of New Metal Complexes Incorporating Schiff Base.

A Schiff base ligand of -vanillin and 4-aminoazobenzene and its transition metal complexes of Ni(II), Co(II), Zn(II), Cu(II), Mn(II), and Zr(IV) were prepared under microwave irradiation as a green approach compared to the conventional method. The structures of new compounds have been characterized and elucidated via elemental and spectroscopic analyses. In addition, magnetic susceptibility, electron spin resonance, and electronic spectra of the synthesized complexes explained their geometrical structures.

Sulfur-Decorated Ni-N-C Catalyst for Electrocatalytic CO Reduction with Near 100 % CO Selectivity.

Developing highly efficient electrocatalysts for electrochemical CO reduction (ECR) to value-added products is important for CO conversion and utilization technologies. In this work, a sulfur-doped Ni-N-C catalyst is fabricated through a facile ion-adsorption and pyrolysis treatment. The resulting Ni-NS-C catalyst exhibits higher activity in ECR to CO than S-free Ni-N-C, yielding a current density of 20.

Fosfomycin and Its Derivatives: New Scale Inhibitors for Oilfield Applications.

Aminomethylenephosphonate-based scale inhibitors (SIs) have been widely studied and recognized for several decades to mitigate various oilfield scales. However, most of these compounds afforded several drawbacks, such as poor biodegradability and intolerance with the production system. As environmental regulations become more rigid, new production chemicals must adhere to certain criteria to qualify for use in the oil and gas industry, particularly in areas with strict regulations, such as the Norwegian Sea.

Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole-Indole Hybrids.

The molecular hybridization concept has recently emerged as a powerful approach in drug discovery. A series of novel indole derivatives linked to the pyrazole moiety were designed and developed a molecular hybridization protocol as antitumor agents. The target compounds (- and -) were prepared by the reaction of 5-aminopyrazoles (-) with -substituted isatin (,) and 1-indole-3-carbaldehyde (), respectively.

Synthesis and Antiscaling Evaluation of Novel Hydroxybisphosphonates for Oilfield Applications.

Organophosphorous compounds are still widely used as potential scale inhibitors in the upstream oil and gas industry, particularly in squeeze treatments as they have good adsorption properties on rock and are easily detectable. However, most phosphonate-based scale inhibitors have some drawbacks, such as poor biodegradability and various incompatibilities with the production system. The low toxicity of bisphosphonates motivated us to test a series of aliphatic and aromatic hydroxybisphosphonates as new oilfield scale inhibitors for calcium carbonate (calcite) and barium sulfate (barite) scales.

Design, Synthesis and Antitumor Evaluation of Novel Pyrazolopyrimidines and Pyrazoloquinazolines.

A series of -aryl-7-aryl-pyrazolo[1,5-]pyrimidines ⁻ and -aryl-pyrazolo[1,5-]quinazolines ⁻ were designed and synthesized via the reaction of 5-aminopyrazoles ⁻ with enaminones ⁻ or , respectively. The new compounds were screened for their in vitro antitumor activity toward liver (HepG-2) and breast (MCF-7) human cancer cells using 3-[4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-tetrazolium bromide MTT assay. From the results, it was found that all compounds showed dose-dependent cytotoxic activities against both HepG-2 and MCF-7 cells.

Ultrasound-assisted synthesis of novel 1,2,3-triazoles coupled diaryl sulfone moieties by the CuAAC reaction, and biological evaluation of them as antioxidant and antimicrobial agents.

A series of 1,2,3-triazoles coupled diaryl sulfone containing compounds were synthesized by the copper-catalyzed azide-alkyne 1,3-dipolar cycloaddition (CuAAC) reaction in benign solvents under ultrasound irradiation. In situ formation of azides from α-bromoketones together with the CuAAC reaction in one pot allowed safe handling and good availability of azides for the development of a small library of compounds. The sonication reduced reaction time and increased yields compared to otherwise same conditions.

Ultrasound assisted synthesis of some new 1,3,4-thiadiazole and bi(1,3,4-thiadiazole) derivatives incorporating pyrazolone moiety.

Novel substituted 1,3,4-thiadiazole and bi(1,3,4-thiadiazole) were synthesized from reaction of 1-methyl-5-oxo-3-phenyl-2-pyrazolin-4-thiocarbox-anilide with a series of different hydrazonyl halides or N,N'-diphenyl-oxalodihydrazonoyl dichloride. The reactions were carried out under both conventional and ultrasonic irradiation conditions. In general, improvement in rates and yields were observed when reactions were carried out under sonication compared with classical condition.