This research evaluates the environmental and health risks linked to potentially toxic elements (PTEs) and PAHs along the western coast of the Gulf of Suez, Egypt. This study investigated the concentration of 16 PAH compounds in the Suez Gulf, revealing significantly higher levels than the EU (0.20 µg/L) and US (0.
View Article and Find Full Text PDFThe impact of LRRK2 variants on the risk of Parkinson's disease in Egyptians remains unknown. We examined 1210 Egyptians (611 PD patients and 599 controls) from 16 governorates across Egypt for 12 LRRK2 pathogenic variants. The p.
View Article and Find Full Text PDFDue to water shortages and the potential impact of Ethiopia's new dam on the Nile River, Egypt is seeking new water resources. This study assesses the drinking water quality and associated risks from potentially toxic elements (PTEs) in the Quaternary aquifer (QA) in Beni-Suef, Egypt. Using a comprehensive approach, including PHREEQC geochemical modeling, ionic ratios, multivariate statistical analyses, and the integrated weight water quality index (WQI), the study evaluated the sources of ion contamination and the mixing of Nile water with QA.
View Article and Find Full Text PDFBackground: Bone marrow-derived mesenchymal stem cells (BM-MSCs) have recently attracted great attention due to their crucial anti-inflammatory and regenerative properties. This work aims to examine the curative impact of intra-articular injection of BM-MSCs-derived exosomes in ameliorating osteoarthritis (OA) progression in rats and to explore the interaction between circular RNA of Yes-associated protein 1 () and microRNA-21 () in the rat knee joints.
Methodology: Gene expression , , toll-like receptor-7 (), aggrecan, and collagen type II were evaluated by quantitative reverse transcription polymerase chain reaction (qRT-PCR) in the rat articular tissues.
The current study integrates remote sensing, machine learning, and physicochemical parameters to detect hydrodynamic conditions and groundwater quality deterioration in non-rechargeable aquifer systems. Fifty-two water samples were collected from all water resources in Siwa Oasis and analyzed for physical (pH, T°C, EC, and TDS) chemical (SO , HCO , NO , Cl, CO , SiO, Mg, Na, Ca, and K), and trace metals (AL, Fe, Sr, Ba, B, and Mn). A digital elevation model supported by machine learning was used to predict the change in the land cover (surface lake area, soil salinity, and water logging) and its effect on water quality deterioration.
View Article and Find Full Text PDFDistributed power generation systems may necessitate connecting multiple independent energy sources that employ various converter topologies. A recent development in this field is the emergence of impedance source converters, offering the ability to deliver buck-boost functionality within a single stage. The split-source inverter (SSI) has been introduced as a novel choice in between this family.
View Article and Find Full Text PDFBackground: Zonisamide (ZNS) has shown some efficacy in motor symptoms of PD; however, more evidence is lacking, and its effects on nonmotor symptoms (NMSs) and quality of life (QoL) remain to be investigated. This randomized double-blinded placebo-controlled crossover study investigated the effect of ZNS on motor and NMS symptoms and QoL in advanced PD.
Methods: PD patients with Hoehn and Yahr stage ≥ 2 ("On" state) and at least 2 h off time daily were randomized to groups: ZNS 25 mg, ZNS 50 mg and placebo.
This study assessed the environmental and health risks associated with heavy metals in the water resources of Egypt's northwestern desert. The current approaches included the Spearman correlation matrix, principal component analysis, and cluster analysis to identify pollution sources and quality-controlling factors. Various indices (HPI, MI, HQ, HI, and CR) were applied to evaluate environmental and human health risks.
View Article and Find Full Text PDFThe study evaluated the use of Chlorella vulgaris for bioremediating hydroponic wastewater and producing biomass under different cultivation modes and to explore the economic implications of microalgal biofuels. Total nitrogen (TN) removal efficiency was 98.5% in mixotrophic conditions and 96% in heterotrophic conditions, and total phosphorus (TP) was completely removed (>99%) in both cultivation conditions.
View Article and Find Full Text PDFIntroduction: COVID-19 is a novel pandemic that has had a profound impact on global physical and psychological health. We aimed to investigate the impact of COVID-19 on stress, sleep quality, and insomnia among South Valley University students in Egypt during the quarantine period.
Material And Methods: A questionnaire, including the Pittsburgh sleep quality index, the insomnia severity index, the perceived stress scale and COVID-19 fear index was distributed to the undergraduate students through the online platforms of South Valley University during the period of 1st to 15th June 2020.
Aims: To study the effect of direct renin inhibitor (aliskiren) on the renal function during acute and chronic partial ureteral obstruction (PUO) in rat solitary kidney.
Main Methods: Sixty male Sprague-Dawley rats were randomly allocated into three groups (20 rats each); sham, PUO and aliskiren groups. Right nephrectomy was performed in all groups.
Manganese-containing mica (Mn-mica) was synthesized at 200 °C/96 h using Mn-carbonate, Al-nitrate, silicic acid, and high KOH concentration under hydrothermal conditions. Mn-mica was characterized and tested as a new adsorbent for the removal of methyl orange (MO) dye from aqueous solutions. Compared to naturally occurring mica, the Mn-mica with manganese in the octahedral sheet resulted in enhanced MO uptake by four times at pH 3.
View Article and Find Full Text PDFSurfactant-modified exfoliated Fayum clay (CTAB-EC) obtained after chemical treatment with a CTAB/HO solution was further decorated with magnetic FeO nanoparticles (MNP). The final nanocomposite (MNP/CTAB-EC) was characterized by XRD, SEM, FTIR, TEM and its adsorptive capability against a model cationic dye, crystal violet (CV), was evaluated. A comparison of the adsorption performance of the raw clay and its modified counterparts using HO, CTAB, CTAB/HO or MNP indicated that the adsorption capacity of MNP/CTAB-EC was the highest for CV removal at pH 8.
View Article and Find Full Text PDFObjective: The aim of this study was to examine the effect of some natural compounds against multidrug-resistant bacteria.
Methods: Forty-three bacterial strains were collected. Disc diffusion and minimum inhibitory concentration (MIC) tests were carried out for natural compounds including quercetin, , , and .
Background: Availability of validated Parkinson's disease (PD) questionnaires in languages spoken in Africa will enable the conduct of epidemiological studies.
Objective: The aims of the current study were to develop cross-cultural translated and validated Arabic and French versions of a PD screening questionnaire, and determine its diagnostic accuracy for recognition of parkinsonism in early and moderate-advanced PD in three countries (Cameroon (French), Egypt (Arabic), and Nigeria (English)).
Methods: This cross-sectional study screened 159 participants (81 PD and 78 controls) using the PD screening questionnaire.
Descending necrotizing mediastinitis [DNM] is a serious complication of odontogenic infections, being associated with a high mortality rate. The diagnosis, classification, and management depend on computed tomography [CT] findings. Incision, drainage, and debridement represent the principal management.
View Article and Find Full Text PDFSynthesis and spectrothermal characterization of new fabricated pyrazinamide complexes with metal [Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and Hg(II)] salts are reported. The structural chemistry of these complexes is achieved via elemental analysis, spectral (UV, visible, and IR), thermal (DTA and TGA) as well as magnetic susceptibility. In these new octahedral complexes (Zn complex is tetrahedral), pyrazinamide acts as a bidentate ligand.
View Article and Find Full Text PDFHeart Surg Forum
September 2019
Background: Rheumatic heart disease (RHD) is the most common cardiac disease in pregnancy in developing countries with the mitral valve being the most affected. In this study, the results of surgical intervention in pregnant women presented with acute malfunctioning mechanical mitral valve were discussed.
Methods: All patients underwent emergency redo mitral valve replacement due to acute malfunctioning mechanical mitral valve during pregnancy in a single center between January 2005 and December 2017.
In the current study, calcination and thermo-chemical methods were applied in treatment of the processed diatomite fraction (<45 μm), which containing nearly 82.6 wt.% of the raw Egyptian diatomaceous earth.
View Article and Find Full Text PDFObjective: This study aimed to determine the prevalence of subclinical enthesopathy in patients with psoriasis using power Doppler ultrasonography (PDUS) and its association with other disease parameters.
Material And Methods: A total of 50 patients with psoriasis (31 females) aged 19-70 years underwent a thorough clinical examination that included assessment of body mass index (BMI) and psoriasis area and severity index (PASI) score. Measurements of inflammatory markers, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), serum uric acid, and plain radiography of the heels, knees, and sacroiliac joints were performed for all patients.
Background: One of the foodborne pathogens is Listeria monocytogenes, which causes serious invasive illness in elderly and immunocompromised patients, pregnant women, newborns and infants ranking second after salmonellosis because of its high case fatality rate. Listerial cow mastitis marked by abnormal milk, increased cell counts and reduced production has not been reported. Therefore, apparently healthy cows can be reservoirs of L.
View Article and Find Full Text PDFIntroduction: Laser and light-based procedures provide a good and safe modality for treatment of active acne lesions when used properly.
Aim: To compare the clinical efficacy of intense pulsed light (IPL) versus 1,064 long-pulsed Neodymium:Yttrium-Aluminum- Garnet (Nd: YAG) in treatment of facial acne vulgaris.
Materials And Methods: Seventy four patients recruited between June 2013 and August 2014 was enrolled in this controlled, single-blind, split-face clinical trial.
Levamisole (LEVA) and garlic are prevalent immunomodulators in humans and animals. Therefore, the present study aimed to examine the immunomodulatory effects of LEVA and garlic oil (GO) alone or in combination on the immune response of Wistar rats. A total of 24 male Wistar rats were allocated into four equal groups: Control group, which was given ad libitum access to food and water; and groups 2‑4, which were orally administered LEVA [2.
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