Background: The SARS-CoV-2 virus's frequent mutations have made disease control with vaccines and antiviral drugs difficult; as a result, there is a need for more effective coronavirus drugs. Therefore, detecting the expression of various diagnostic biomarkers, including ncRNA in SARS-CoV2, implies new therapeutic strategies for the disease.
Aim: Our study aimed to measure NEAT-1, miR-374b-5p, and IL6 in the serum of COVID-19 patients, demonstrating the correlation between target genes to explore the possible relationship between them.
Purpose: Early-onset colorectal cancer (EOCRC) is a rising health problem. The incidence of EOCRC has increased over the past 2 decades all over the world. Reports from Egypt since the 1990s have reported a higher incidence among young populations with no identifiable risk factors.
View Article and Find Full Text PDFBackground: Ulcerative colitis (UC) has emerged as an accelerated-incidence chronic condition. UC has been identified as a precancerous lesion for colorectal cancer. Up-to-date genomic research revealed the value of many noncoding RNAs (ncRNAs) in UC pathogenesis, diagnosis, and prognosis.
View Article and Find Full Text PDFis a long noncoding RNA that works as an enhancer for the Interferon-gamma (IFN-γ) transcript. (growth arrest-specific 5) is a lncRNA that is associated with glucocorticoid resistance. Aberrant expressions of and are directly linked to numerous autoimmune disorders but their levels in childhood ITP are still obscure.
View Article and Find Full Text PDFVariations of the mechanical properties of red blood cells that occur during their life span have long been an intriguing task for investigations. The research presented is based on noninvasive monitoring of red blood cells of different ages performed by scanning acoustic microscopy with magnitude and phase contrast. The characteristic signature of fixed cells from groups of three different ages fractionated according to mass density is obtained from the acoustic microscope images, with the data represented in polar graphs.
View Article and Find Full Text PDFThe self-diffusion behavior of the polyethylene glycol (PFG) polymer in bovine nasal cartilage was studied by pulsed-field gradient (PFG) nuclear magnetic resonance (NMR). PFG NMR allows the determination of the mean square displacement of molecules in a given diffusion time (in the range of a few milliseconds up to seconds), monitors distances in micrometer scales and has the advantage of being non-invasive. Moreover the application of pfg nmr does not require concentration gradients In a previous study, PFG NMR was used to investigate the self-diffusion behavior of the PEG polymer in cartilage at very highconcentrations.
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