Publications by authors named "Mohamed Elshayeb"
Article Synopsis
- Chronic spontaneous urticaria (CSU) is a complex condition, and this study explored the connection between serum zonulin levels, a marker for "leaky gut," and CSU among patients.
- The study included 97 CSU patients and 87 healthy controls, revealing that CSU patients had significantly lower zonulin levels than the controls (median of 2.93 ng/ml versus 3.92 ng/ml).
- Although a positive correlation was found between serum zonulin and C-reactive protein, no significant relationship was established between zonulin levels and disease activity or immunoglobulin E levels, suggesting factors like diet and medication could impact zonulin levels in CSU patients.
Asthma is a heterogeneous disease that affects a large proportion of the global population and is distinguished by airway hyperresponsiveness to direct and indirect stimulations. It is a multifactorial disease that is triggered by heredity and environmental causes. Tenascin C (TNC) is an extracellular matrix glycoprotein that promotes inflammatory cell migration from the interstitium to the airways.
View Article and Find Full Text PDFObjectives: The main risk factor for poor graft outcomes is refractory acute rejection and its consequences. In this study, we compared the efficacy of antithymocyte globulins versus other antirejection strategies in reversing refractory acute graft rejection after living donor renal transplant.
Materials And Methods: We retrospectively reviewed the records of 745 patients who received living-donor kidney transplants and experienced acute rejection episodes at Mansoura Urology and Nephrology Center in Egypt over the past 20 years.
Work related asthma (WRA) refers to asthma induced by exposure to sensitizing agents and/or irritants in the workplace leaving health and economic consequences. Early diagnosis can improve the prognosis of WRA permitting sometimes full recovery. This study aimed to assess the prevalence of WRA among Egyptian adult agriculture workers.
View Article and Find Full Text PDFBackground: Composition of gut microbiota has recently been suggested as a key factor persuading the pathogenesis of numerous human diseases including hepatic cirrhosis.
Objective: To evaluate the potential impact of Lactobacillus acidophilus and Bifidobacterium bifidum microbiota on the progression of hepatic histopathological changes among patients with non-cirrhotic chronic hepatitis C (HCV) infection with different viral load. Additionally, to assess fecal composition of Lactobacillus acidophilus ATCC-4356 and Bifidobacterium bifidum ATCC-11863 microbiota genotypes MATERIAL AND METHODS: This study was carried out on 40 non-cirrhotic chronically infected HCV patients, and 10 healthy-controls.
Article Synopsis
- Chronic spontaneous urticaria (CSU) is a common skin condition affecting many people, with around 90% of cases being idiopathic, and nearly half thought to involve autoimmune mechanisms.
- The study examined the presence of specific T regulatory cells (CD4+CD25highFOXP3+) in CSU patients and their link to autologous serum skin tests (ASST).
- Results showed that CSU patients had lower levels of these T regulatory cells compared to healthy individuals, supporting the idea that CSU is related to immune system issues and suggesting potential avenues for new treatments.
Recently, many researchers are interested in studying asthma COPD overlap (ACO) group features. Sensitization to Aspergillus has been linked to increased severity of asthma; however, limited data is available about fungal sensitization in ACO group. This study was designed to determine the prevalence of Aspergillus fumigatus (A.
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