Publications by authors named "Mohamed El Karroumi"

Introduction And Importance: Occult breast cancer (OBC) is defined as a clinically recognizable metastatic carcinoma arising from an undetectable primary breast tumor.

Presentation Of Case: We report in this work 2 cases of occult breast cancer treated at the Mohammed VI center of onco-gynecology of the CHU of Casablanca.

Clinical Discussion: Significant advances in breast imaging have occurred since its description, decreasing its incidence.

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Introduction And Importance: Squamous cell carcinoma associated with primary neuroendocrine carcinoma (NEC) of the breast, also known as composite tumor, is an extremely rare malignancy with a very poor prognosis.

Presentation Of Case: We report the case of a patient treated in our department for primary neuroendocrine carcinoma of the breast associated with squamous cell carcinoma by radical surgery.

Clinical Discussion: Diagnosis is based on histology and, above all, immunohistochemistry.

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Parietal metastasis is a very rare secondary location of papillary thyroid carcinoma. It associated with poor prognosis. We report a case of a 61-year-old woman with parietal metastasis from papillary thyroid carcinoma.

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Article Synopsis
  • The study investigates the relationship between hypermethylation of the BRCA1/2 promoter genes and breast cancer in women, focusing on how this relates to age and tumor stage.
  • It analyzes DNA from 50 biopsies of Moroccan women with breast cancer, revealing that 62% of samples showed BRCA1 hypermethylation, while BRCA2 was negative.
  • The findings suggest that BRCA1 methylation is more prevalent in women over 47 years old, indicating that age could play a significant role in the progression of breast cancer.
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