[Another case of the rare complications of chronic lymphocytic leukemia: angioedema].

Angioedema is a rare but may be serious (laryngeal edema). This is a recurrent edema, subcutaneous and/or submucosal, whose cause is a hereditary or acquired deficiency in C1 inhibiteur (C1 inhibitor fraction of complement). We present the case of a 56 years old patient who showed recurrent episodes of swelling of the face and hands in association with chronic lymphocytic leukemia stage A.

Leflunomide-induced toxic epidermal necrolysis in a patient with rheumatoid arthritis.

Introduction: Leflunomide is an immunomodulating agent with proven efficacy in rheumatoid arthritis. Although its overall safety profile is good, a few cases of toxic epidermal necrolysis have been reported.

Case Report: This 36-year-old woman had rheumatoid arthritis that proved refractory to sulfasalazine and methotrexate, which were used successively in combination with symptomatic drugs.

[Cutaneous metastasis revealing a testicular choriocarcinoma].

Skin is an uncommon site of metastatic disease when compared to other organs or sites in the body. Occasionally, cutaneous metastasis may be the first clinical manifestation of a clinically silent, visceral malignancy of unknown origin. We report the case of a 25 year old man with a single perineal reddish nodule.