[Fatal hemophagocytic syndrome that reveals retroviral infection].

Hemophagocytic syndrome is a rare disease with a severe prognosis. Infections are a classic cause of hemophagocytic syndrome. Hemophagocytic syndromes secondary to HIV are rare, and those that reveal HIV infection are even rarer.

[Macrophage activation syndrome revealing colon carcinoma About a case].

Macrophage activation syndrome is a state of hyper-inflammation that results from increased secretion of proinflammatory cytokines, responsible of the inappropriate activation and proliferation of cells from the lymphohistiocyte lineage. It associates clinical signs, biological abnormalities and images of haemophagocytosis. It is a rare but serious attack, that can be "primary" or "secondary" to an infection, neoplasia, or autoimmune disease.

Atypical chronic myeloid leukemia BCR-ABL 1 negative: A case report and literature review.

Atypical chronic myeloid leukemia (aCML), negative is a rare myelodysplastic syndrome/myeloproliferative neoplasm for which no current standard of care exists. The blood smear of patients with aCML showed prominent immature granulocytosis, and granulocytic dysplasia. We admitted a 58-year-old man with splenomegaly, hyperleukocytosis, anemia, and thrombocytopenia; then cytology, cytogenetic and molecular biology analysis of bone morrow were performed and the diagnosis of aCML was made according to 2016 World Health Organization diagnostic criteria.