Thymus algeriensis Boiss. et Reut., a north African endemic plant species: genetic diversity and population structure as assessed by molecular markers, a pioneer step for conservation implications.

Background: Thymus algeriensis Boiss. et Reut. is one of the most widespread North African species of the genus Thymus L.

Variation in Phenolic Content, Antioxidant Activity and Alpha-amylase and Acetylcholinesterase Inhibitory Capacities of Different Extracts from Tunisian Satureja barceloi (Willk) L.

The antioxidant activity and the anti-α-amylase and anti-acetylcholinesterase capacities of secondary metabolites from different organs (roots, stems, leaves and flowers) of Tunisian Satureja barceloi were determined. The variation in the distribution of phenolic metabolites among roots, stems, leaves and flowers extracts of S. barceloi with various solvent systems (methanol, ethyl acetate, hexane and distilled water) has not been characterized before.

Hochst. ex Boiss. from the Northern Region of Saudi Arabia: Essential Oil Profiling, Plant Extracts and Biological Activities.

Hochst. ex Boiss is an occasional plant species in the Northern region of Saudi Arabia. The shrub is favored on sandy desert wadis, gypsaceous substrate, and sandy gravel desert.

Molecular signature of phylogenetic relationships and demographic history of Tunisian Mactra stultorum: Evidence from mitochondrial and nuclear DNA data.

The genetic structure of Mactra stultorum is inferred from partial sequence of a mitochondrial cox1gene and of the internal transcribed spacer region ITS1. The samples with two colors of shell (white and brown) were collected from three sites belonging to the Tunisian coasts: Kalaât El Andalous (KA) and Soliman (SM) and Gabes (GM)). The phylogenetic trees obtained from the 2 markers are similar and subdivided samples into 3 distinct clades; clade (1) regrouped GM, clade (2) regrouped KS (KS contains samples from SM and KAa) and clade (3) is formed by KAb.

Allium sativum mitigates oxidative damages induced by Microcystin-LR in heart and liver tissues of mice.

Microcystins (MCs) are hepatotoxic cyanotoxins implicated in several incidents of human and animal toxicity. Microcystin-(Lysine, Arginine) or MC-LR is the most toxic and encountered variant of MCs where oxidative stress plays a key role in its toxicity. This study investigated the oxidative damages induced in the liver and heart of Balb/C mice by an intraperitoneal injected acute dose of MC-LR.

Ethnopharmacological study of natural products used for traditional cancer therapy in Algeria.

Traditional and complementary medicine constitutes an important, and often underestimated, source of healthcare for multiple diseases including cancer. However, little is known about the ethnomedical knowledge and practices in Northern Africa. The main objective of this study is to identify and analyze the variety of natural products used in Algerian ethnopharmacology for cancer therapy.

Differentiation of Phenolic Composition Among Tunisian Boiss. et Reut. () Populations: Correlation to Bioactive Activities.

Twelve Tunisian populations growing wild in different bioclimatic zones, extending from the subhumid to the upper-arid bioclimates, were compared regarding their phenolic composition and their ability to serve as antioxidant, anti-acetylcholinesterase, and antibacterial agents. A significant variation of phenol profile was observed between the analyzed populations, as assessed by ultra-high-performance liquid chromatography coupled with a diode array detector and an electrospray mass spectrometer (UHPLC-DAD-ESI/MS) technique. Rosmarinic acid was the main phenolic compound in most populations (383.

Polyphenolic Profiling, Quantitative Assessment and Biological Activities of Tunisian Native (L.) Huds.

Phenolic profiling of ten plant samples of (L.) Huds. collected from different bioclimatic areas of Tunisia, was for the first time carried out by using a fast ultra-high-performance liquid chromatography (UHPLC)-high resolution tandem mass spectrometry (HRMS/MS) method on a Q Exactive platform equipped with an electrospray ionization (ESI) source.

Euphorbia honey and garlic: Biological activity and burn wound recovery.

Currently, chronic wounds and microbial resistance to antibiotics have led to search new healing agents. Combinations of natural products are widely practiced in traditional medicine and exhibited synergistic activity with increased efficacy in treating several pathologies. This study assays the antioxidant, synergistic antimicrobial and burn wound healing activities of Euphorbia honey and Allium sativum (garlic).

Genetic relationships among subspecies of Capparis spinosa L. from Tunisia by using ISSR markers.

In Tunisia, Capparis spinosa L. is widely distributed in different geographic areas. Although it has been extensively studied morphologically, the phylogenetic relationships by using molecular markers among Capparis taxa are still unclear.

Phytochemical profile and biological activities of (Desf.)DC.: a desert aromatic shrub widespread in Northern Region of Saudi Arabia.

The present study describes the chemical composition of the essential oil of different plant parts of ; and biological activities of plant extract and essential oils. Apiol was found to be the major component of the oil (between 65.73% and 74.

Relationship between chemotypic and genetic diversity of natural populations of Artemisia herba-alba Asso growing wild in Tunisia.

A total of 80 individuals collected from eight populations growing wild in different geographic zones were considered to assess the intraspecific variability of essential oil composition, genetic diversity and population structure of Artemisia herba-alba. The essential oil composition varied significantly between populations. Essential oil profiles were classified into four chemotypes (trans-sabinyl acetate, α-thujone/trans-sabinyl acetate, camphor and α-thujone/camphor/β-thujone).

Essential Oil Variability in Natural Populations of Artemisia campestris (L.) and Artemisia herba-alba (Asso) and Incidence on Antiacetylcholinesterase and Antioxidant Activities.

The intraspecific variability of Artemisia herba-alba and A. campestris essential oils and the evaluation of their antioxidant and antiacetylcholinesterase activities were determined. Artemisia herba-alba essential oil was found rich in camphor (19.

Essential Oils of Myrtaceae Species Growing Wild in Tunisia: Chemical Variability and Antifungal Activity Against Biscogniauxia mediterranea, the Causative Agent of Charcoal Canker.

The chemical composition of five Eucalyptus species and five Myrtus communis L. populations was investigated using GC/MS and GC-FID. For Eucalyptus essential oils, 32 compounds, representing 88.

Bioactive compounds from Hypericum humifusum and Hypericum perfoliatum: inhibition potential of polyphenols with acetylcholinesterase and key enzymes linked to type-2 diabetes.

Context: Natural products are reported to have a wide spectrum of pharmacological properties such as antimicrobial, anti-inflammatory and anti-cholinesterase. The genus Hypericum (Hypericaceae) is a source of a variety of molecules with different biological activities, notably hypericin and various phenolics.

Objectives: The goals of the present work were the determination of total phenolic and flavonoid content, hypericin and hyperforin concentration as well as the evaluation of biological of Hypericum humifusum L.

Asteraceae and Essential Oils Trigger Apoptosis and Cell Cycle Arrest in Promastigotes.

We report the chemical composition and anti- and antioxidant activity of L. and - Asso. essential oils (EOs).

Ecological systems as computer networks: Long distance sea dispersal as a communication medium between island plant populations.

Ecological systems are known to exchange genetic material through animal species migration and seed dispersal for plants. Isolated plant populations have developed long distance dispersal as a means of propagation which rely on meteorological such as anemochory and hydrochory for coast, island and river bank dwelling species. Long distance dispersal by water, in particular, in the case of water current bound islands, calls for the analogy with computer networks, where each island and nearby mainland site plays the role of a network node, the water currents play the role of a transmission channel, and water borne seeds as data packets.

Bioactive compounds contents, antioxidant and antimicrobial activities during ripening of Prunus persica L. varieties from the North West of Tunisia.

Bioactive molecules from fruits of four varieties of Prunus persica at different stages of ripening (green, small orange, red) were studied. For example, contents on polyphenols (20.36mg GAE/g FW) and flavonoids (0.

Genetic diversity and phylogenetic analysis of two Tunisian bivalves (Mactridae) Mactra corallina (Linnaeus, 1758) and Eastonia rugosa (Helbling, 1799) based on COI gene sequences.

A partial sequence of mitochondrial cytochrome c oxidase subunit I (COI) was used as a genetic marker for a genetic diversity and phylogenetic analysis (DNA barcoding) of two Mactridae species, Mactra corallina and Eastonia rugosa, collected from the Tunisian coast. These Mactridae species could be distinguished by DNA barcoding techniques and they will be considered as monophyletic clades with the Neighbor-Joining (NJ) tree. The genetic structure detected that E.

Modeling hydrochory effects on the Tunisian island populations of Pancratium maritimum L. using colored Petri nets.

Hydrochory, the seed dispersal by water, is a strategy used by many aquatic and some terrestrial plants to move into areas appropriate for establishment. In this paper we model the hydrochory effects on the Tunisian island populations of Pancratium maritimum L. using colored Petri nets.

Determination of phytochemicals and antioxidant activity of methanol extracts obtained from the fruit and leaves of Tunisian Lycium intricatum Boiss.

A comparative analysis of methanol extracts from fruit and leaves of Lycium intricatum Boiss., a Solanaceous shrubbery with the potential to become a high-value crop, was performed by means of liquid chromatography with photodiode array and electrospray ionisation mass spectrometric detection (LC/PDA/ESI-MS). The total phenolic (TPC), anthocyanin (TAC) and flavonoid (TFC) contents as well as the antioxidant capacity measured by four complementary methods were performed for each sample.

Essential oil composition and antibacterial activity of Origanum vulgare subsp. glandulosum Desf. at different phenological stages.

Variation in the quantity and quality of the essential oil (EO) of wild population of Origanum vulgare at different phenological stages, including vegetative, late vegetative, and flowering set, is reported. The oils of air-dried samples were obtained by hydrodistillation. The yield of oils (w/w%) at different stages were in the order of late vegetative (2.

Essential-oil composition of the Tunisian endemic cypress (Cupressus sempervirens L. var. numidica TRAB.).

The essential oils isolated from leaves, wood, and cones of the Tunisian endemic cypress Cupressus sempervirens L. var. numidica Trab.

Myrtus communis L. infusions: the effect of infusion time on phytochemical composition, antioxidant, and antimicrobial activities.

In traditional medicine, myrtle (Myrtus communis L.) is frequently consumed as an infusion and decoction. In this study, we investigate the phenolic and volatile compositions and antioxidant and antibacterial activities of leaf infusions prepared during 3 different times.

Variation of volatiles in Tunisian populations of Thymbra capitata (L.) Cav. (Lamiaceae).

Volatiles from 14 wild Tunisian populations of Thymbra capitata (=Thymus capitatus Hoffmanns. et Link=Coridothymus capitatus Rchb.f.