Publications by authors named "Mohamed Alsabbagh"
Article Synopsis
- * Patients with severe COVID-19 often show low levels of certain immune cells (like CD4+ and CD8+ T cells), and severe cases can lead to a "cytokine storm," where an overproduction of inflammatory proteins can worsen the condition.
- * Current treatments focus on both antiviral drugs to stop the virus and immunomodulators to manage the immune response, with ongoing research into other effective agents to better control the disease.
TRADD is an adaptor for TNFR1-induced apoptosis and NFκB activation. However, TRADD-deficient mice undergo normal development and contain normal lymphoid populations, which contrasts with an embryonic defect in mice lacking FADD, the shared adaptor mediating apoptosis. Recent studies indicate FADD suppresses embryonic necroptosis mediated by RIPK1.
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