Publications by authors named "Mohamed Ali H Jawad-Makki"
Article Synopsis
- - The study investigates the effects of extracorporeal membrane oxygenation (ECMO) on airway complications in patients with severe primary graft dysfunction (PGD3) following lung transplantation, highlighting the potential benefits of early ECMO use.
- - Results showed that patients on veno-venous ECMO (VV-ECMO) had lower instances of PGD3 and reduced risk of chronic allograft dysfunction compared to those solely on mechanical ventilation (MV).
- - The findings suggest VV-ECMO may help prevent ischemic reperfusion injury and lower the severity of airway complications post-transplantation, indicating a need for further research to understand the underlying mechanisms.
Tranexamic acid (TXA) has long been utilized in spine surgery and can be administered through intravenous (IV) and topical routes. Although, topical and IV administration of TXA are both effective in decreasing blood loss during spine surgery, complications like deep vein thrombosis (DVT) and pulmonary embolism have been reported with the use of intravenous TXA (ivTXA). These potential complications may be mitigated through the use of topical TXA (tTXA).
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- Male MS-NASH mice were fed a high-fat diet for 16 weeks, with some receiving red algae-derived minerals and others comparing with obeticholic acid and a control group on a low-fat diet.
- Results showed that high-fat diet mice had increased body and liver weight, liver enzyme levels, and severe liver issues including inflammation and steatosis, while mineral supplementation appeared to moderate these effects.
- The study concludes that multi-mineral supplementation in mice on a high-fat diet lessens liver toxicity and provides significant protection against tumor formation and severe liver damage compared to those solely on a high-fat diet.
Article Synopsis
- * A trial with 30 participants compared Aquamin against calcium alone and a placebo over 90 days, examining colonic biopsies for specific protein expressions before and after the treatment.
- * Results showed Aquamin reduced Ki67 (a marker for cell proliferation) and slightly increased CK20 (a differentiation marker), with broader protein expression changes compared to calcium alone, suggesting potential benefits for colonic health.
Article Synopsis
- Aquamin, a natural multi-mineral product rich in calcium and magnesium, was studied to see if it could improve the colonic barrier in patients with ulcerative colitis (UC) by utilizing colonoid cultures from their biopsies.
- The study involved incubating these colonoids with or without Aquamin for two weeks, analyzing changes in barrier proteins and structure using advanced microscopy and proteomic techniques.
- Results showed some positive effects, including increased expression of differentiation-related proteins and tight junctions, as well as improved structural features, suggesting that Aquamin may enhance barrier function in UC-affected tissue.