Publications by authors named "Mohamed Al-Kindi"
In this study, bacteria residing in the gut of the rice weevils ( L.) (Coleoptera: Curculionidae) feeding on aflatoxin-contaminated corn kernels were isolated and evaluated for their ability to suppress and to remove/degrade aflatoxin B1 (AFB1). Four morphologically distinct gut-associated bacterial isolates were isolated and identified as (RWGB1), (RWGB2), (RWGB3), and (RWGB4) based on 16S rRNA gene sequence analysis.
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- * Adding elemental sulfur effectively reduced the pH of biochar from 8.1 to 7.2, particularly when paired with vermicompost, and improved nutrient availability and microbial activity.
- * The combination of biochar, sulfur, and compost/vermicompost was identified as a sustainable approach to boost biochar's fertility and manage its alkalinity, making it more suitable for arid environments.
Introduction: Circulating microparticles (MP) are being described as potential biomarkers for disease activity in a variety of conditions including sickle cell anemia (SCA). However, relatively little is known about the influence of spleen status on MP levels in patients with SCA.
Methods: Using a prospective study design we characterize circulating MP in 144 patients with SCA in steady state by assessing their cellular origin and their relationships to spleen status defined by clinical and imaging findings.
Argulus foliaceus (Linnaeus, 1758) is a member of the branchiuran family Argulidae, a group comprising parasitic "fish lice". A. foliaceus is distributed worldwide and causes major economic impacts for cultured freshwater fish globally.
View Article and Find Full Text PDFOxidative stress plays a pivotal role in the development of diabetes and hyperglycaemia. The protective effects of natural extracts against diabetes are mainly dependent on their antioxidant and hypoglycaemic properties. Broccoli () exerts beneficial health effects in several diseases including diabetes; however, the mechanism has not been elucidated yet.
View Article and Find Full Text PDFBreast cancer (BC) is the most common cause of cancer-related death worldwide. Although platinum-based drugs (PBDs) are effective anticancer agents, responsive patients eventually become resistant. While resistance of some cancers to PBDs has been explored, the cellular responses of BC cells are not studied yet.
View Article and Find Full Text PDFObjectives: Marine organisms are a rich source of bioactive molecules with potential applications in medicine, biotechnology and industry; however, few bioactive compounds have been isolated from organisms inhabiting the Arabian Gulf and the Gulf of Oman. This study aimed to isolate and screen the anti-cancer activity of compounds and extracts from 40 natural products of marine organisms collected from the Gulf of Oman.
Methods: This study was carried out between January 2012 and December 2014 at the Sultan Qaboos University, Muscat, Oman.
Background: Azoxymethane (AOM) is a potent carcinogenic agent commonly used to induce colon cancer in rats; the cytotoxicity of AOM is considered to mediate oxidative stress. This study investigated the chemopreventive effect of three natural extracts [pomegranate peel extract (PomPE), papaya peel extract (PapPE) and seaweed extract (SE)] against AOM-induced oxidative stress and carcinogenesis in rat colon.
Methods: Eighty Sprague-Dawley rats (aged 4 weeks) were randomly divided into 8 groups (10 rats/group).
Aim: To study whether N-acetyltransferase 2 (NAT2) genotypes and phenotypes are associated with increased risk factor for gastric cancer in Omani patients and to study the clinico-pathological correlations and the prognostic significance of NAT2.
Methods: Genomic DNA was extracted from peripheral blood of 100 gastric cancer patients and 100 control subjects. NAT2 genotyping was performed using DNA sequencing.