Publications by authors named "Mohamed Adel El-Eshmawy"

Article Synopsis
  • Oxidative stress arises when reactive free radicals accumulate in cells, and the MnSOD enzyme helps detoxify these harmful oxygen species.
  • The study examined the role of the SOD2 (rs4880; p.Val16Ala) genetic variant in 254 children, including 127 with asthma (both atopic and non-atopic) and 127 healthy controls.
  • Results showed that the SOD2*rs4880 variant is significantly linked to a reduced incidence of bronchial asthma in children, suggesting it may confer protective effects against the condition.
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The renin-angiotensin-aldosterone system has an indispensable function in the uteroplacental circulation, placental growth, and blood pressure optimization. The angiotensin I converting enzyme (ACE) gene is a critical integrator for electrolyte balance, and water retention, along with inhibiting preeclampsia. The main goal of this pertaining study is to assess the contribution of ACE*(Ins/Del) variant with the susceptibility for preeclampsia with focus on the severity of the disease among gestational hypertensive women.

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Background: The prevalence rate of breast carcinoma (BC) among multiple ethnic populations required more explanations to understand the pathogenesis mechanisms for the development of this type of cancer. The principal purpose of this work is to validate the correlation of the CCND1 (c.723G > A; rs9344) variant with an increased risk of breast carcinoma.

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