Publications by authors named "Mohamed A Shahin"

Purpose: BRCA gene mutations (BRCAm) have an impact on patients' characteristics and clinical outcomes of ovarian cancer (OC). The frequency and patterns of BRCAm vary among countries and ethnicities. There are limited data from Saudi Arabia (SA); thus, this study aims to determine the frequency, pattern, and impact on patient characteristics and outcomes of BRCAm OC compared to wild-type BRCA (BRCAw) in Saudi women.

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Mitigation of erosion along the riverbanks is a global challenge. Stabilisers such as cement can control erosion, but it risks the river ecology. This paper presents the erosion characteristics of riverbank soil treated with two biological stabilisers that alleviate the ecological cost.

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This study determined the effects of antioxidant supplementation and storage time at cool temperatures on the characteristics of epididymal camel spermatozoa. Camel testes were collected at the abattoir after animal slaughtering and kept at 4 °C during transportation and until processing (max 6 h). Spermatozoa were retrieved and diluted with SHOTOR extender, split in aliquots, supplemented with the following antioxidants: 200 μm/mL vitamin E, 1.

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Article Synopsis
  • There are challenges in preserving camel semen, including high viscosity and reduced motility post-ejaculation.
  • This study found that using nanoparticles of zinc and selenium (ZnONPs and SeNPs) in semen extenders significantly improved the quality of cryopreserved dromedary camel epididymal spermatozoa.
  • The supplementation with these nanoparticles led to better sperm motility, vitality, and integrity, while also enhancing protective antioxidant levels and reducing cell damage during freezing and thawing.
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Background: The increase in tumor markers with negative or equivocal conventional imaging modalities represents a serious dilemma in the follow-up of previously treated cancer patients. Positron emission tomography/computed tomography (PET/CT) has emerged as a useful tool in oncological imaging in staging and restaging of most cancers.

Objective: This study explored the potential role of ¹⁸F-fluorodeoxyglucose (FDG) PET/CT in the detection and localization of tumor recurrence in cancer patients with increasing serum tumor markers and negative or equivocal conventional imaging modalities.

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