Prosthetic Applications of Short Dental Implants in Limited Bone Height Cases: A Review Article.

The decision to rehabilitate insufficient alveolar bone height with short implants is considered an effective treatment. Complicated surgical procedures such as ridge augmentation, vestibuloplasty, and sinus lifting are usually accompanied by high risks such as membrane injury, hemorrhage, nerve affection, and increased time needed for implant treatment with unpredictable healing time. Short dental implants allow for faster treatment and decrease the need for complicated surgeries that are usually associated with standard dental implants, as in all four and all six concepts.

Molecular Docking, Bioinformatic Analysis, and Experimental Verification for the Effect of Naringin on ADHD: Possible Inhibition of GSK-3β and HSP90.

One of the most abundant and growing neurodevelopmental disorders in recent decades is attention deficit hyperactivity disorder (ADHD). Many trials have been performed on using drugs for the improvement of ADHD signs. This study aimed to detect the possible interaction of naringin with Wnt/β-catenin signaling and its putative anti-inflammatory and protective effects in the mouse ADHD model based on bioinformatic, behavioral, and molecular investigations.

Combined Dietary and Essential Oil Enhances the Growth, Immunity, Antioxidant Capacity and Intestinal Health of Nile Tilapia.

The dietary presence of feed additives is crucial for boosting fish growth and immunity. Accordingly, this feeding trial aimed to investigate the effects of the separate and concurrent dietary supplementation of (SP) and bitter lemon () peel essential oil (LEO) on the growth, immunity, antioxidant capacity, and intestinal health of Nile tilapia (). Four groups of male Nile tilapia were employed.

Evaluation of the effect of thermocycling on the trueness and precision of digitally fabricated complete denture bases.

Background: While many denture base materials are currently available on the market, little data exists regarding their dimensional stability after exposure to the oral environment. This study aimed to evaluate the effect of thermocycling on the trueness and precision of milled, 3-dimensional (3D)-printed, and conventional digitally fabricated complete denture bases (CDBs).

Methods: A completely edentulous maxillary stone model was scanned to generate a standard tessellation language (STL) file; this was imported into metal-milling-machine software (Redon Hybrid CAD-CAM metal milling machine, Redon, Turkey) to produce a metal model for fabricating 30 CDBs.

Evaluating the Impact of Various Treatment Modalities on the Chewing Efficiency of Anterior Disc Displacements of Temporomandibular Joint Disorder Cases: A Comparative Study.

Aim: Internal disc displacement of the temporomandibular joint (TMJ) is identified by an anomaly between the condylar-disc assembly, which, in many cases, may lead to discomfort and malfunction of the chewing function. The study's objective was to assess the effects of four distinct treatment approaches on temporomandibular disorder cases with anterior disc displacements focusing on their chewing efficiency.

Materials And Methods: One hundred participants suffering from reducible TMJ disc displacement were selected for enrollment in the study.

Effect of Duplication Techniques on the Fitting Accuracy of CAD-CAM Milled, 3D-Printed, and Injection-Molded Mandibular Complete Denture Bases.

Background: Digital technology has been introduced in prosthodontics, and it has been widely used in denture duplication instead of a conventional denture duplication technique. However, research comparing different denture duplication techniques and how they affect the fitting accuracy of the denture base is scarce.

Objectives: The aim was to assess the impact of duplication techniques on the accuracy of the fitting surface of computer-aided design and manufacturing (CAD-CAM) milled, 3D-printed, and injection-molded complete denture bases (CDBs).

Effect of Different Occlusal Tooth Forms of Mandibular Overdenture Retained by an Immediate Loaded Single Implant on the Masticatory Efficiency and Oral Health-Related Quality of Life.

Aim: To study the masticatory efficacy and oral health-related quality of life (OHRQoL) of participants wearing a mandibular overdenture retained by an immediate loading single implant with different occlusal tooth forms.

Materials And Methods: For this nonrandomized controlled trial study, 27 edentulous participants were selected and randomly divided into three groups ( = 9) based on occlusal tooth forms of the mandibular implant overdenture (MIOD). Group I: participants received an MIOD with an anatomical tooth form; Group II: participants received an MIOD with a semianatomical tooth form; and Group III: participants received an MIOD with a nonanatomical tooth form.

Novel fluorescence approach for trace quantification of levonorgestrel in breast milk based on click reaction with benzonitrofurazan azide (NBD-AZ).

Although the great importance of oral contraceptive agents in birth control, their existence in breast milk became a cause for concern, since infant exposure to these hormones is associated with many health problems. Consequentially, developing a sensitive bioanalytical method for monitoring their concentrations in breast milk is an urgent demand to examine the safety or the risk of these compounds on infants. Levonorgestrel is one of the most common contraceptive hormones under concern.

Impact of different chemical denture cleansers on the properties of digitally fabricated denture base resin materials.

Purpose: To compare the impact of three different chemical denture cleansers (CDCs) (Corega, chlorhexidine, and hydrogen peroxide) on the surface roughness, microhardness, and color stability of 3D-printed, computer-aided design and computer-aided manufacturing (CAD-CAM) milled, and heat-polymerized denture base material (DBM).

Materials And Methods: A total of 420 disc-shaped specimens (10 ± 0.1 × 2 ±0.

Efficacy of Occlusal Splints and Low-Level Laser Therapy on the Mandibular Range of Motion in Subjects with Temporomandibular Joint Disc Displacement with Reduction.

Aims And Objectives: The study was carried out to evaluate the efficacy of four conservative therapeutic modalities on the mandibular range of motion (MRM) in subjects with anterior disc displacement with reduction (ADDwR) of the temporomandibular joint (TMJ).

Materials And Methods: One hundred patients (64 women and 36 men) were selected, and randomly distributed into four groups. Group I: Subjects receiving behavioral therapy (BT).

4-Azido-7-nitrobenzoxadiazole as innovative clickable fluorescence probe for trace and selective quantification of ethinylestradiol in human plasma.

Quantification of ethinylestradiol (EE) in biological matrices is challenging as it is a very potent drug with a very low C (75 pg.ml ). Despite the high sensitivity of fluorometric methods, the detection of EE was confined because its structure exhibited very limited fluorescence.

Betanin improves motor function and alleviates experimental Parkinsonism via downregulation of TLR4/MyD88/NF-κB pathway: Molecular docking and biological investigations.

Parkinson's disease (PD) is a progressive neuroinflammatory and degenerative disease. In this study, we investigated the neuroprotective action of betanin in the rotenone-induced Parkinson-like mice model. Twenty-eight adult male Swiss albino mice were divided into four groups: Vehicle, Rotenone, Rotenone + Betanin 50 mg/kg, and Rotenone + Betanin 100 mg/kg.

Structure-based design of novel melanin-concentrating hormone receptor-1 ligands based on saturated nitrogen-containing heterocycles.

Melanin Concentrating Hormone (MCH) receptor is a G protein-coupled receptor (GPCR) with two subtypes R1 and R2. MCH-R1 is involved in the control of energy homeostasis, feeding behavior and body weight. Many studies have proved that administration of MCH-R1 antagonists significantly reduces food intake and causes weight loss in animal models.

Evaluation of Surface Properties and Elastic Modulus of CAD-CAM Milled, 3D Printed, and Compression Moulded Denture Base Resins: An Study.

Objectives: This study evaluated the surface roughness, surface hardness, and elastic modulus of CAD-CAM (Computer-aided design/computer-aided manufacturing) milled, three-dimensional printed and conventional compression-moulded denture base resins.

Materials And Methods: Thirty specimens (65*10*3 mm) were fabricated and divided into 3 groups (10 for each group) according to the type of denture base resin, Group I contained specimens of milled denture base resin, Group II contained specimens of 3-dimensional printed denture base resin, Group III contained specimens of polymethyl methacrylate heat cured denture base resin. The surface roughness of all specimens was evaluated using an atomic force microscope.

Corrigendum: leaf powder dietary inclusion differentially modulates the antioxidant, inflammatory, and histopathological responses of normal and -infected mono-sex Nile tilapia ().

[This corrects the article DOI: 10.3389/fvets.2022.

Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial GSK3/PK6 with Activity against Blood Stage Parasites In Vitro.

Essential plasmodial kinases GSK3 and PK6 are considered novel drug targets to combat rising resistance to traditional antimalarial therapy. Herein, we report the discovery of as a dual GSK3/PK6 inhibitor active against blood stage 3D7 parasites. To establish structure-activity relationships for PK6 and GSK3, 52 analogues were synthesized and assessed for the inhibition of GSK3 and PK6, with potent inhibitors further assessed for activity against blood and liver stage parasites.

The synergetic effect of Bacillus species and Yucca shidigera extract on water quality, histopathology, antioxidant, and innate immunity in response to acute ammonia exposure in Nile tilapia.

Acute ammonia toxicity suppresses the immune function and enhances the inflammatory pathways in Nile tilapia. The aim of this study was to compare the effect of Bacillus strains probiotic mixture (BS) or Yucca shidigera liquid extract (YSE) alone or their combination in water treatment and in reliving toxicity of an acute ammonia exposure in Nile tilapia through the assessment of fish immune response, inflammatory pathway, oxidative stress response with respect to the histopathological changes, gene expression, enzymes levels and phagocytosis. Five groups were used; the 1st and 2nd groups fed the basal diet; the 3rd group fed basal diet with BS in water, 4th group fed basal diet and supplemented with YSE in water and 5th group received a combination of BS and YSE.

3D-Printed Microfluidics Potential in Combating Future and Current Pandemics (COVID-19).

Coronavirus disease (COVID-19) emerged in China in December 2019. In March 2020, the WHO declared it a pandemic leading to worldwide lockdowns and travel restrictions. By May, it infected 4,789,205 and killed 318,789 people.

Impact of Nanoparticles Additions on the Strength of Dental Composite Resin.

Objective: This study aimed to evaluate the effect of nanoparticles, zirconium dioxide (ZrO), titanium dioxide (TiO), and silicon dioxide (SiO), on flexural strength (FS), hardness, and wear resistance of light cured dental composite resin.

Materials And Methods: 210 rectangular and disc-shaped composite resin specimens were fabricated with dimensions (25 × 2 × 2 ± 0.03 mm) and (6×4 ± 0.

Leaf Powder Dietary Inclusion Differentially Modulates the Antioxidant, Inflammatory, and Histopathological Responses of Normal and -Infected Mono-Sex Nile Tilapia ().

This study aimed to detect the impact of leaf powder dietary inclusion on the antioxidant and innate immune responses of mono-sex Nile tilapia fingerlings. A total of 180 fingerlings were allocated in a random method into three groups with triplicate each. One group (1 group) received the control diet (basal diet (BD) free of moringa) and the other groups (2 and 3) fed BD containing leaf powder at 5 and 10% of the diet, respectively.