Diabetic microaneurysms detected by fluorescein angiography spatially correlate with regions of macular ischemia delineated by optical coherence tomography angiography.

Purpose: To characterize the relationship between diabetic macular ischemia (DMI) delineated by optical coherence tomography angiography (OCTA) and microaneurysms (MAs) identified by fundus fluorescein angiography (FFA).

Methods: Patients with diabetic retinopathy (DR) who underwent OCTA and FFA were retrospectively identified. FFA images were cropped and aligned with their respective OCTA images using i2k Align Retina software (Dual-Align, Clifton Park, NY, USA).

Novel CYP1B1 mutations and a possible prognostic use for surgical management of congenital glaucoma.

Aim: To identify CYP1B1 gene mutations and evaluate their possible role as a prognostic factor for success rates in the surgical management of Egyptian congenital glaucoma patients.

Methods: Totally 42 eyes of 29 primary congenital glaucoma patients were operated on with combined trabeculotomy/trabeculectomy with mitomycin-C and followed up at 1d, 1wk, 1, 6 and 12mo postoperatively. Genomic DNA was extracted from peripheral blood leukocytes.

Goldmann versus Disposable Applanation Tonometer Tips in Glaucoma Patients and Normal Subjects.

Purpose: To assess agreement of intraocular pressure (IOP) measured with Goldmann applanation and disposable Luneau SA applanation prisms in glaucoma patients compared with normal subjects.

Methods: In a prospective comparative study, one eye per primary open-angle glaucoma (POAG) patient was measured for IOP using Goldmann and disposable Luneau SA (Tonojet) applanation tonometry prisms. Glaucoma patients found with IOP < 21 mmHg were compared to an age-matched group of normal subjects.

Personal A-constant in relation to axial length with various intraocular lenses.

Purpose: To study the relationship between the axial length and personal A-constant for the 1-piece Tecnis (Abbott ZCB00), AcrySof MA60AC (Alcon) and the Quatrix aspheric preloaded (CROMA) intraocular lenses (IOL).

Materials And Methods: Patients matching the inclusion criteria were further subdivided according to the implanted IOL in this prospective comparative study. The obtained refractive outcomes were introduced into the formula installed in the biometry machine (Humphrey model 820 ultrasonic biometer) to obtain the personal A-constant for each eye.

Pneumatic trabecular bypass versus trabeculotomy in the management of primary congenital glaucoma.

Background: The optimal surgical management in primary congenital glaucoma (PCG) remains a subject of debate. The aim of this study was to assess efficacy of pneumatic trabecular bypass (PTB) in comparison to conventional trabeculotomy (T) in the treatment of PCG.

Methods: In a prospective comparative experimental study, one eye per child suffering from PCG underwent either PTB or T.

Non-penetrating filtration surgery versus trabeculectomy for open-angle glaucoma.

Background: Glaucoma is the second commonest cause of blindness worldwide. Non-penetrating glaucoma surgeries have been developed as a safer and more acceptable surgical intervention to patients compared to conventional procedures.

Objectives: To compare the effectiveness of non-penetrating trabecular surgery compared with conventional trabeculectomy in people with glaucoma.

Surgically induced astigmatism following glaucoma surgery in Egyptian patients.

Purpose: The altered visual function induced by changes in corneal curvature following filtration surgery is distressing to patients. The aim of this study was to evaluate surgically induced astigmatism following trabeculectomy in comparison with deep sclerectomy.

Methods: In a prospective interventional comparative study, patients with primary open-angle glaucoma were randomly allocated to either group A or B; deep sclerectomy with mitomycin C 0.

Eye trauma during the 2011 Egyptian revolution.

Background: Cairo university hospitals are at the heart of Cairo with close proximity to Tahrir (Liberation) square and had received the vast majority of casualties during the Egyptian revolution. The aim of this study was to analyze the eye injuries during the uprising.

Design: Retrospective cohort study.

Pneumatic trabecular bypass (PTB): pilot study.

Purpose: To evaluate the initial efficacy of Pneumatic trabecular bypass (PTB) for open angle glaucoma patients.

Design: Prospective case series study.

Methods: Ten eyes of 10 patients meeting the inclusion criteria had been operated for PTB.

First versus second eye intravitreal ranibizumab therapy for wet AMD.

Purpose: To evaluate the short-term visual outcomes after intravitreal ranibizumab for wet age-related macular degeneration, when used in first eyes (good vision in the untreated eye) compared with second eyes (significant visual impairment in the untreated eye).

Methods: Seventy-five consecutive patients who received intravitreal ranibizumab injection were divided into Group A, comprising 35 first eyed patients and Group B, comprising 40 second eyes. Visual acuity and contrast sensitivity was compared before treatment, and 3 months after the 3rd injection.