Flavonoid constituents and protective efficacy of (Blanco) leaves ethanolic extract on thioacetamide-induced liver injury rats.

Oxidative stress leads to deleterious processes in the liver that resulted in liver diseases. To evaluate antioxidant activity and hepatoprotective potential of ethanolic leaves extract of against hepatic dysfunction induced by thioacetamide (TAA). Flavonoid constituents were isolated from the ethanol extract by chromatographic techniques and identified by the spectroscopic analyses.

A new acylated flavone glycoside, antioxidant and antimicrobial activities from Saudi Hochst. ex A. DC (Ebenaceae) leaves.

Phytochemical investigation of leaves resulted in the isolation of new acylated flavone isoscutellarein 7--(4'''--acetyl)--allopyranosyl(1''' → 2'')--glucopyranoside (), along with eight known flavonoid metabolites, luteolin 3',4',6,8-tetramethyl ether (), luteolin 4'---neohesperidoside (), luteolin 7---glucoside (), luteolin (), quercetin (), quercetin 3---glucoside (), quercetin 3---rhamnoside (), and rutin (). Their structures were identified by analysis of spectroscopic (UV, NMR, and MS) data, as well as by acid hydrolysis for the isolated glycosides. The antioxidant activity of metabolites was determined by the DPPH radical-scavenging assay.

Pentagalloyl Glucose, a Major Compound in Mango Seed Kernel, Exhibits Distinct Gastroprotective Effects in Indomethacin-Induced Gastropathy in Rats Modulating the NO/eNOS/iNOS Signaling Pathway.

Gastric ulcers are a common health disorder that affect up to 10% of the world's population. The gastroprotective potential of pentagalloyl glucose (PGG) against indomethacin-induced ulcer in rats and the possible underlying mechanisms were investigated. Gastric ulceration was induced by indomethacin (single dose, 60 mg/kg).

A New Polyoxygenated Flavonol Gossypetin-3---d-Robinobioside from (Hook.) D. Dietr. and In Vivo Hepatoprotective, Anti-Inflammatory, and Anti-Ulcer Activities of the Leaf Methanol Extract.

A hitherto unknown polyoxygenated flavonol robinobioside (gossypetin-3---d-robinobioside) was isolated from the leaves of along with thirteen known phenolic secondary metabolites. The isolated compounds were characterized using spectroscopic analysis, including 1D and 2D NMR and mass spectrometry (MS) analyses. The extract reduced the level of liver damage in CCl₄-induced liver injury in rats.

Flavonoid constituents of Dobera glabra leaves: amelioration impact against CCl-induced changes in the genetic materials in male rats.

Context: Dobera glabra (Forssk.) Poir (Salvadoraceae) is a highly valued tree with diverse importance as special mineral sourced feed and a folkloric tool for forecasting droughts. However, there are no reports on its phytochemical and biological investigations.

Myricitrin and bioactive extract of Albizia amara leaves: DNA protection and modulation of fertility and antioxidant-related genes expression.

Context: Albizia species are reported to exhibit many biological activities including antiovulatory properties in female rats and antispermatogenic and antiandrogenic activities in male rats.

Objective: The present study investigates the flavonoids of Albizia amara (Roxb.) B.

A new alpha-methylanthraquinone glucoside from Emex spinosus.

A new alpha-methylanthraquinone glucoside, laccaic acid D 8-o-beta-D-glucoside, and six known anthraquinones have been isolated from the aqueous alcoholic extract of Emex spinosus (L.) Campd. (Polygonaceae), together with two known flavonol glycosides.