Publications by authors named "Mohamed A Al-Fatimi"

The hydrodistilled essential oil obtained from the dried leaves of Myrtus communis, collected in Yemen, was analysed by GC-MS. Forty-one compounds were identified, representing 96.3% of the total oil.

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Sixteen methanolic extracts obtained from thirteen plant species, selected either from ethnobotanical or chemotaxonomical data, were screened for their antileishmanial activity against Leishmania amazonensis. The cytotoxic activity against normal peritoneal macrophages from normal BALB/c mice was also determined. Eight extracts had IC50 values ranging from <12.

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Article Synopsis
  • The study focused on the essential oil extracted from Pulicaria stephanocarpa leaves, analyzing its composition and bioactivities using GC-MS.
  • The oil contained 83 identified compounds, with (E)-Caryophyllene being the most abundant at 13.4%, along with several other notable compounds.
  • The oil exhibited effective antimicrobial activity against Gram-positive bacteria and Candida albicans, demonstrated significant antioxidant capabilities with a DPPH IC50 of 330 microg/mL, and showed a 47% inhibition of acetylcholinesterase (AChE) at a concentration of 200 microg/mL.
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Synopsis of recent research by authors named "Mohamed A Al-Fatimi"

  • - Mohamed A Al-Fatimi's research primarily focuses on the chemical characterization and biological activities of essential oils and plant extracts, specifically from regions in Yemen and Soqotra.
  • - Findings from his studies indicate significant antimicrobial, antioxidant, and anticancer properties in essential oils derived from plants like Myrtus communis and Pulicaria stephanocarpa, suggesting their potential in therapeutic applications.
  • - Al-Fatimi has also explored the antileishmanial activity of various medicinal plants, identifying several extracts with promising effects against Leishmania amazonensis, which may contribute to the development of natural remedies for leishmaniasis.

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