Histological and histomorphometric evaluation of hydroxyapatite-based biomaterials in surgically created defects around implants in dogs.

Background: The present study evaluated histologically and histometrically the efficacy of micro-, nano-, or mixed-composite of hydroxyapatite (HA) graft in treatment of surgically created defects around dental implants in mongrel dogs.

Methods: Immediate implant was used after extraction of the lower third premolar in mongrel male dogs. Critical-size defects were created in intact proximal alveolar bone to each implant.