Publications by authors named "Mohamadreza Kiarsi"
Background: Implantable cardioverter-defibrillators (ICDs) have been established for primary and secondary prevention of fatal arrhythmias and effectively reduce the rate of sudden cardiac death (SCD). This study aims to evaluate the indications and effectiveness of ICD for primary and secondary prevention of SCD.
Materials And Methods: This retrospective study was conducted on 229 patients (136 for primary and 93 for secondary prevention) with ICD implantations in Imam Khomeini Hospital, Ahvaz, between 2017 and 2020.
Article Synopsis
- * 268 participants are randomly assigned to wear ECS with varying pressure levels—either therapeutic (25-30 mm Hg) or sham (≤10 mm Hg)—while receiving standard VVS treatment and monitored for a year.
- * This study is significant as it addresses the lack of evidence regarding ECS as a treatment for VVS, aiming to fill an important gap in understanding how to manage this condition.
Comparison of Outcomes with Midodrine and Fludrocortisone for Objective Recurrence in Treating Syncope (COMFORTS trial): Rationale and design for a multi-center randomized controlled trial.
Arya Aminorroaya Hamed Tavolinejad Saeed Sadeghian Arash Jalali Farshid Alaeddini Mohamadreza Kiarsi
Am Heart J
July 2021
Article Synopsis
- The COMFORTS trial investigates the effectiveness of pharmacological treatments (midodrine and fludrocortisone) in managing vasovagal syncope (VVS) alongside lifestyle modifications.
- A total of 1375 patients will be randomized into three groups to receive either medication or no medication, with follow-ups at various intervals to assess outcomes.
- The primary goal is to determine how long it takes for patients to experience their first syncopal episode after starting treatment, while secondary outcomes include recurrence rates and quality of life improvements.