Radiolabeled nanoceria probes may reduce oxidative damages and risk of cancer: a hypothesis for radioisotope-based imaging procedures.

Low-dose ionizing radiations are commonly utilized in medical centers for diagnostic imaging procedures. Unfortunately, the absorption of ionizing radiation generates reactive chemical species that could damage cells. In diagnostic radioisotope-based imaging procedures, the radiological exposures by gamma emitter imaging probes such as radioactive technetium ((99m)Tc) could express low risk of cancer.

Impact of various color LED flashlights and different lighting source to skin distances on the manual and the computer-aided detection of basal cell carcinoma borders.

Background/aims: Quantitative analysis based on digital skin image has been proven to be helpful in dermatology. Moreover, the borders of the basal cell carcinoma (BCC) lesions have been challenging borders for the automatic detection methods. In this work, a computer-aided dermatoscopy system was proposed to enhance the clinical detection of BCC lesion borders.

Monte Carlo simulations and radiation dosimetry measurements of 142Pr capillary tube-based radioactive implant (CTRI): a new structure for brachytherapy sources.

Objective: Previously, a promising β(-)-emitting praseodymium-142 glass seed was proposed for brachytherapy of prostate cancer. In accordance with the previous study, a (142)Pr capillary tube-based radioactive implant (CTRI) was suggested as a source with a new structure to enhance application of β(-)-emitting radioisotopes such as (142)Pr in brachytherapy.

Methods: Praseodymium oxide powder was encapsulated in a glass capillary tube.

Preparation of radioactive praseodymium oxide as a multifunctional agent in nuclear medicine: expanding the horizons of cancer therapy using nanosized neodymium oxide.

Objective: Many studies have attempted to assess the significance of the use of the β(-)particle emitter praseodymium-142 ((142)Pr) in cancer treatment. As praseodymium oxide (Pr(2)O(3)) powder is not water soluble, it was dissolved in HCl solution and the resultant solution had to be pH adjusted to be in an injectable radiopharmaceutical form. Moreover, it was shown that the nanosized neodymium oxide (Nd(2)O(3)) induced massive vacuolization and cell death in non-small-cell lung cancer.

Scope of nanotechnology-based radiation therapy and thermotherapy methods in cancer treatment.

The main aim of nanomedicine is to revolutionize the health care system and find effective approaches to fighting fatal diseases. Therapeutic beams, which are employed in radiation therapy, do not discriminate between normal and cancerous cells and must rely on targeting the radiation beams to specific cells. Interestingly, the application of nanoscale particles in radiation therapy has aimed to improve outcomes in radiation therapy by increasing toxicity in tumors and reducing it in normal tissues.

Bremsstrahlung parameters of praseodymium-142 in different human tissues: a dosimetric perspective for (142)Pr radionuclide therapy.

Objective: Praseodymium-142 [T 1/2 = 19.12 h, [Formula: see text] = 2.162 MeV (96.

Internal radiotherapy techniques using radiolanthanide praseodymium-142: a review of production routes, brachytherapy, unsealed source therapy.

Radionuclides of rare earth elements are gaining importance as emerging therapeutic agents in nuclear medicine. β(-)-particle emitter 142Pr [T (1/2) = 19.12 h, E(-)β = 2.