Publications by authors named "Mohamad Sitheek Abdul Rahman"
Article Synopsis
- Durian fruit contains various nutrients and has been studied for its potential anticancer properties, particularly against human leukemia cells (HL-60).
- The methanolic extract from durian was found to induce DNA damage and apoptosis in HL-60 cells, confirmed by comet and DNA fragmentation assays.
- The extract causes cell cycle arrest in specific phases and promotes apoptosis by increasing pro-apoptotic proteins while decreasing anti-apoptotic proteins, supporting its anticancer mechanism.
