Study of single nucleotide polymorphism of vascular endothelium factor in patients with differentiated thyroid cancer.

Background: Genetic alterations and high levels of the vascular endothelial growth factor (VEGF) are presumptive risk factors for differentiated thyroid cancer (DTC).

Objective: This work aims to study the presence of - 634G/C polymorphism of vascular endothelial growth factor (rs2010963) and its' serum level in patients with DTC and comparing these results with those of the control subjects.

Material And Method: The study was a retrograde case-control study that included seventy patients with DTCin addition to seventy apparently healthy control subjects.