It is widely accepted that cancer, the second leading cause of death, is a morbidity with big impacts on the global health. In the last few years, chemo-therapeutic treatment continually induces alone most lengthy consequents, which is extremely harmful for the physiological and psychological health of the patients. In the present research, we discuss the recent techniques for employed for extraction, and quantitative determination of such compounds in pharmaceutical, and biological specimens.
View Article and Find Full Text PDFNanostructured metal oxides, such as zinc oxide (ZnO), are considered as excellent materials for the fabrication of highly sensitive and selective electrochemical sensors and biosensors due to their good properties, including a high specific surface area, high catalytic efficiency, strong adsorption ability, high isoelectric point (IEP, 9.5), wide band gap (3.2 eV), biocompatibility and high electron communication features.
View Article and Find Full Text PDFThis review summarizes the progress that has been made in the past ten years in the field of electrochemical sensing using nanomaterial-based carbon paste electrodes. Following an introduction into the field, a first large section covers sensors for biological species and pharmaceutical compounds (with subsections on sensors for antioxidants, catecholamines and amino acids). The next section covers sensors for environmental pollutants (with subsections on sensors for pesticides and heavy metal ions).
View Article and Find Full Text PDFThis study describes a kinetic spectrophotometric method for accurate, sensitive and rapid determination of cisplatin in biofluids. The developed method is based on the inhibitory effect of cisplatin on the oxidization of Janus Green by bromate in acidic media. The change in absorbance as the criteria of the oxidation reaction was followed spectrophotometrically.
View Article and Find Full Text PDFResearch and development in the applied sciences at the atomic or molecular level is the order of the day under the domain of nanotechnology or nano-science with enormous influence on nearly all areas of human health and activities comprising diverse medical fields such as pharmacological studies, clinical diagnoses, and supplementary immune system. The field of nano-dentistry has emerged due to the assorted dental applications of nano-technology. This review provides a brief introduction to the general nanotechnology field and a comprehensive overview of the synthesis features and dental uses of nano-materials including current innovations and future expectations with general comments on the latest advancements in the mechanisms and the most significant toxicological dimensions.
View Article and Find Full Text PDFOne of the most studied topics in analytical chemistry and physics is to develop bio-sensors. Aptamers are small single-stranded RNA or DNA oligonucleotides (5-25 kDa), which have advantages in comparison to their antibodies such as physicochemical stability and high binding specificity. They are able to integrate with proteins or small molecules, including intact viral particles, plant lectins, gene-regulation factor, growth factors, antibodies and enzymes.
View Article and Find Full Text PDFThis study is on current developments concerning ferrocene (FC) and its derivatives on the basis of electrochemical biosensors and sensors. The distinct physiochemical characteristics of FC have enabled the development of new sensor devices, specifically electrochemical sensors. Several articles have focused on the implementation of FC as an electrode constituent while discussing its electrochemical behavior.
View Article and Find Full Text PDFFolic acid (FA) as one of the water-soluble vitamins contributes to the construction of healthy cells, as FA deficiency is one of the leading causes of anaemia. Based on reports, reduced folate level can lead to development of carcinogenesis. Hence, its analysis from the clinical point of view is highly demanded.
View Article and Find Full Text PDF