Measurement of total CO in microliter samples of urine and other biological fluids using infrared detection of CO.

The purpose of this study is to describe a low-cost and simply made instrument capable of measuring the total CO content of microliter volumes of biological fluids utilizing a commercially available CO sensor based on a NDIR detector. The described instrument is based on transformation of dissolved HCO to CO by acidification and subsequent measurement of the produced CO. The instrument has a linear response in the range 0.