Publications by authors named "Moelo Malahleha"
Background: There are gaps in uptake of, adherence to, and persistence in the use of preexposure prophylaxis for human immunodeficiency virus (HIV) prevention among cisgender women.
Methods: We conducted a phase 3, double-blind, randomized, controlled trial involving adolescent girls and young women in South Africa and Uganda. Participants were assigned in a 2:2:1 ratio to receive subcutaneous lenacapavir every 26 weeks, daily oral emtricitabine-tenofovir alafenamide (F/TAF), or daily oral emtricitabine-tenofovir disoproxil fumarate (F/TDF; active control); all participants also received the alternate subcutaneous or oral placebo.
Article Synopsis
- Incidence rates of respiratory syncytial virus-associated lower respiratory tract illness (RSV-LRTI) in infants were assessed in low- and middle-income countries (LMICs) as existing data was limited.
- The study followed 2,094 infants from 10 LMICs over one year, using surveillance and testing to identify cases during the COVID-19 pandemic.
- Results indicated a low incidence of RSV-LRTI (1.5% of infants) and all-cause lower respiratory tract infections, likely influenced by reduced viral activity during the pandemic.
Aim: We compared the effect of two different doses of sucrose on neonatal pain scores during venepuncture.
Methods: This randomised crossover study focused on neonates born weighing more than 1000 g from December 2014 to June 2016, who received neonatal intensive care at two hospitals: one in Empangeni, South Africa, and one in Trondheim, Norway. During two consecutive venepuncture procedures, 27 neonates from South Africa and 26 neonates from Norway were randomised to receive 0.