Publications by authors named "Moeen Ul Haq"
Objectives: To explore the landscape of BRCA1/2 mutations in gastric cancer patients.
Methods: Next-generation sequencing (NGS), Sanger sequencing, reverse transcription quantitative polymerase chain reaction (RT-qPCR), Immunohistochemistry, The Cancer Genome Atlas (TCGA), gnomAD, and DAVID.
Results: With 95% of bases boasting a phred score surpassing 30 and a minimum coverage depth of 500X, our NGS approach ensures high-quality data acquisition.
Article Synopsis
- Antibiotic-associated diarrhea (AAD) commonly occurs due to antibiotic treatments disrupting gut microbiota, prompting research into the effectiveness of probiotics to prevent this issue.
- The study aimed to evaluate how effective probiotics are in reducing AAD symptoms in adults compared to a placebo, enrolling 340 participants across various hospitals.
- Results showed that the probiotic group had a significantly lower incidence of AAD (18.23%) compared to the placebo group (31.17%), indicating that probiotics may be beneficial in preventing this complication.
Background: Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, have been increasingly associated with kidney stone disease, posing significant health challenges globally.
Objective: This research sought to determine the causal relationship between kidney stone disease risk and inflammatory bowel disorders.
Methodology: This retrospective cohort study included patients with IBDs, such as ulcerative colitis or Crohn's disease, who were diagnosed at least 18 years of age.
Objectives: Being a checkpoint, the expression level of V-set immunoregulatory receptor (VSIR) serves as an indicator of the extent of immunosuppression. Our objective was to undertake a pan-cancer analysis to examine the expression, genetic alterations, prognosis, and immunologic features associated with VSIR.
Methods: The Cancer Genome Atlas (TCGA), Genotype-Tissue Expression (GTEx), GEPIA2, UALCAN, OncoDB, Human Protein Atlas (HPA), STRING, DAVID, cell culture, clinical sample collection, and reverse transcription quantitative polymerase chain reaction (RT-qPCR) were used.
Palliative care emergencies such as spinal cord compression require prompt diagnosis and treatment to get the best results. Hospitals dealing with these emergencies need to develop pathways of care for these patients based on best evidence derived from hard data. The authors looked at all spinal cord compressions that presented to their hospital over a 10-year period.
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