Publications by authors named "Moe Yamashiro"
Article Synopsis
- The fate of glycoproteins in the endoplasmic reticulum hinges on their folding or degradation, largely influenced by glycan trimming processes.
- Lectin chaperones assist in folding monoglucosylated glycoproteins, while those with trimmed mannoses face degradation through ER-associated mechanisms.
- Recent findings reveal that UGGT1 plays a crucial role in delaying the degradation of misfolded glycoproteins, indicating its central importance in maintaining protein quality control in the ER.
