MLEM deconvolution of protein X-ray diffraction images based on a multiple-PSF model.

In this paper we analyze the degradation of protein X-ray diffraction images by diffuse light distortion (DLD). In order to correct the degradation, a new multiple point spread function (PSF) model is introduced and used to restore X-ray diffraction image data (XRD). Raw PSFs are collected from isolated spots in high-resolution areas on the diffraction patterns which represent the orientation of DLDs.

Stochastic modelling of individual cell growth using flow chamber microscopy images.

In this paper, we analysed individual cell growth images obtained by flow chamber microscopy system. We used replicate flow chamber experiment data as reported by [Elfwing, A., Le Marc, Y.

Adaptive penalty likelihood for reconstruction of multidimensional confocal microscopy images.

In this paper we devise a penalty likelihood with noise constraints method to restore 2D and 3D confocal microscope images. Regularization is a commonly used technique in image restoration to balance restored image quality and noise suppression, but despite this noise is usually amplified. Taking into account common confocal imaging system degradation, we develop an algorithm by using a gradient descent method (PLGDA) to approach the minimum solution of the penalty likelihood equation.

Connection between stochastic and deterministic modelling of microbial growth.

We present in this paper various links between individual and population cell growth. Deterministic models of the lag and subsequent growth of a bacterial population and their connection with stochastic models for the lag and subsequent generation times of individual cells are analysed. We derived the individual lag time distribution inherent in population growth models, which shows that the Baranyi model allows a wide range of shapes for individual lag time distribution.

The DynDom database of protein domain motions.

Unlabelled: A relational database has been developed based on the results from the application of the DynDom program to a number of proteins for which multiple X-ray conformers are available. The database is populated via a web-based tool that allows visitors to the website to run the DynDom program server-side by selecting pairs of X-ray conformers by Protein Data Bank code and chain identifier.

Availability: The website can be found at: http://www.