Publications by authors named "Moe Oguchi"

Article Synopsis
  • Patients with severe acute kidney injury (AKI) in ICUs who undergo continuous venovenous hemodiafiltration (CVVHDF) face high mortality risk, and there's limited research on clinical biomarkers to predict outcomes and guide treatment.* -
  • This study analyzed 133 patients, measuring urinary neutrophil gelatinase-associated lipocalin (NGAL) and plasma IL-6 at various points during CVVHDF; results showed higher NGAL and IL-6 levels in nonsurvivors compared to survivors.* -
  • Findings indicate that urinary NGAL levels may serve as important biomarkers for predicting mortality and the need for renal replacement therapy in patients undergoing CVVHDF, with significant differences observed between success and failure
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Aim: Phenobarbital overdose can cause coma and even death. The consciousness disturbance is often prolonged due to its long half-life. In this study, we investigated the efficacy of direct hemoperfusion (DHP) for the removal of phenobarbital by measuring the blood levels of phenobarbital.

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Continuous venovenous hemodiafiltration is the modality of choice for acute blood purification therapy at almost all medical institutions in Japan. Nafamostat mesilate, an ultrashort-acting anticoagulant, is widely used for anticoagulation. Due to restrictions imposed by national health insurance, Japanese institutions use an effluent flow rate of 15 mL/kg/h, which is lower than the standard effluent flow rate used in the West.

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