Publications by authors named "Moe Haines"
Article Synopsis
- The study presents an optimized workflow for analyzing formalin-fixed, paraffin-embedded (FFPE) patient tissues to uncover molecular insights linked to clinical outcomes, utilizing advanced techniques like Adaptive Focused Acoustics (AFA) and liquid chromatography-tandem mass spectrometry (LC-MS/MS).
- The method allows for the analysis of up to 96 samples, identifying between 8,000-10,000 unique proteins with a high level of quantitative accuracy (<20% median CVs).
- Applied to lung adenocarcinoma FFPE blocks, the workflow demonstrates superior deep proteome coverage and efficiency, significantly contributing to biomarker discovery and proteomic research in archived samples.
