Publications by authors named "Modhurima Mazumder"
Nat Prod Res
October 2024
Article Synopsis
- - The study investigates the anti-inflammatory properties of piperine (PPN) by inducing inflammation in young chicks and administering PPN with various other drugs to compare effects.
- - Results show that PPN effectively reduces inflammation indicators, like licking frequency and paw swelling, in a dose-dependent manner; however, it also reduces the effectiveness of concurrent medications celecoxib (CXB) and ketoprofen (KPN).
- - PPN demonstrates a strong binding affinity to the COX-2 enzyme, suggesting its mechanism of action involves COX-2 inhibition, leading to its anti-inflammatory effects in chicks while competing with other anti-inflammatory drugs.
