Broadband Shortwave Infrared-Emitting Cr- and Ni-Codoped YAlGaO Phosphor with Excellent Thermal Stability for Multifunctional Applications.

Shortwave infrared (SWIR)-emitting materials have emerged as superior light sources with increasing demand for potential applications in noninvasive analysis, night vision illumination, and medical diagnosis. For developing next-generation SWIR phosphor-converted light-emitting diodes (pc-LEDs), the scarcity of intense blue-light-pumped broadband SWIR luminescent materials and poor thermal stability of current Ni-activated phosphors are the ongoing challenges. Here, a blue-light-excitable (440 nm) YAlGaO:Cr,Ni phosphor with ultrawide SWIR emission centered at ∼1430 nm (FWHM ∼264 nm) is reported.

Synthesis of 6-bromo-7-arylaminoisoquinoline-5,8-quinones and its effects on Piscirickettsia salmonis infection in vitro.

Among the most important aquaculture resources for our country, salmon and trout stand out. Their production has increased significantly in recent decades, making them two of the most valuable resources in economic terms. However, high aquaculture production has allowed many pathogens to proliferate, causing infectious diseases and significant production losses.

Oral administration of a new copper (I) complex with coumarin as ligand: modulation of the immune response and the composition of the intestinal microbiota in .

[Cu(NN)]ClO is a copper (I) complex, where NN is an imine ligand 6-((quinolin-2-ylmethylene) amino)-2H-chromen-2-one obtained by derivatization of natural compound coumarin, developed for the treatment of infectious diseases that affect salmonids. In previous research, we showed that the Cu(I) coordination complex possesses antibacterial activity against , providing protection against this pathogen in rainbow trout during challenge assays (with an RPS of 50%). In the present study, the effects of administering [Cu(NN)]ClO to over a 60-days period were evaluated with regard to systemic immune response and its potential to alter intestinal microbiota composition.

Oleogel-based drug delivery for the treatment of periodontitis: current strategies and future perspectives.

Periodontitis is the chronic inflammation of tooth-supporting tissues that leads to loss of tooth support if untreated. Conventional therapy for periodontitis (mechanical removal of microbial biofilm and oral hygiene enforcement) is augmented by anti-microbial and anti-inflammatory drugs. These drugs are frequently delivered locally into the periodontal pocket for maximum efficiency and minimum adverse effects.

[Cu(NN)]ClO, a Copper (I) Complex as an Antimicrobial Agent for the Treatment of Piscirickettsiosis in Atlantic Salmon.

is the pathogen that most affects the salmon industry in Chile. Large quantities of antibiotics have been used to control it. In search of alternatives, we have developed [Cu(NN)]ClO where NN = 6-((quinolin-2-ylmethylene)amino)-2H-chromen-2-one.

Color tunable luminescence in ThO:Er,Yb nanocrystals: a promising new platform for upconversion.

Lanthanide-doped luminescent nanoparticles are an appealing system for many applications in the area of biomedical, solar cell, thermometry, anti-counterfeiting, due to their sensitivity, reliability, high photochemical stability, and high optical transparency in the visible-NIR range. A color-tunable upconversion-luminescence (UCL) in a new low phonon energy ThO host based on modulating sensitizer concentration has been realized in this work and it may work as a potential candidate to replace corrosive and toxic fluoride based hosts in the future. Er-Yb co-doped thoria nanoparticles were prepared using a gel combustion route and their structural and luminescence properties were determined as a function of the Yb concentration.

Development of magnetic La doped AlO core-shell nanoparticle loaded hydrogel for selective recovery of fluoride from aquatic medium.

The selective removal of pollutants from water bodies is regarded as a conciliation between the rapid expansion of industrial activities and need of clean water for sustainability. Fluoride is one such geogenic pollutant, and various materials have already been reported. Developing an efficient field employable material is however a challenge.

Local Structure and Speciation-Driven UO → Sm Energy Transfer for Enhanced Luminescence in LiBO.

Herein, we report the uranyl sensitization of Sm emissions in uranium-codoped LiBO:Sm phosphor. The uranyl speciation in codoped [Sm, U] LTB samples was determined by synchrotron-based extended X-ray absorption fine structure (EXAFS) spectroscopy that revealed two coordination shells for U(VI) ions with bond distances of U-O (∼1.81 Å) and U-O (∼2.

Probing site-selective doping and charge compensating defects in KMgF: insights from a hybrid DFT study.

Design of optoelectronic materials with tunable properties using activators and defect clusters has become one of the prime interests of current research. In this study, detailed Density Functional Theory based calculations have been presented to investigate the geometries and electronic structures of various possible defect clusters using Eu-KMgF as a probe which has numerous technological and industrial applications. Using a more reliable hybrid density functional, we have calculated defect formation energies and thermodynamic transition levels to get knowledge about the site selectivity of Eu.

Gene therapy as a treatment of oral cancer: An insight.

Oral cancer or oral squamous cell carcinoma comprises more than three-fourth of all the malignant neoplasms of the oral cavity. Worldwide, it is the 18 most common malignancy. The patients suffering from cancer usually remains immune to the standard therapies such as surgical resection of tumours, radiotherapy and chemotherapy; however, there can be probabilities of chronic and acute toxicities and secondary malignancies as well.

Characterization and active component identification of Premna herbacea roxb. root extract reveals anti-inflammatory effect and amelioration of imiquimod induced psoriasis via modulation of macrophage inflammatory response.

Background: 1-2.88% of human populations are affected by psoriasis, one type of chronic inflammatory skin disease. Skin thickenings, erythema, scaling in skin are the most important symptoms of psoriasis.

Comprehensive study on the origin of orthorhombic phase stabilization in Gd-doped HfO and DFT calculations.

In recent times, ultra-thin films of hafnium oxide (HfO) have shown ferroelectricity (FE) attributed to the orthorhombic (o) phase of HfO with space group 2. This polar o-phase could be stabilized in the doped thin film of the oxide. In the present work, both polar and non-polar o-phases of HfO could be stabilized in Gd-doped bulk polycrystalline HfO.

Radiation response of YAlO and Nd-YAlO to Swift heavy ions: insight into structural damage and defect dynamics.

Understanding the behavior of a material under irradiation is paramount to its application in the nuclear industry. The present work explores the radiation response of garnet YAlO (YAG) and Nd-substituted YAlO (Nd-YAG) under a 100 MeV Iodine beam at varying fluences to mimic the effect of fission fragments. This is relevant to the potential application of garnet as a host for minor actinide (MA) transmutation (Nd: surrogate for long-lived MA (Am, Np, Cm)).

An ethnographic approach to understand cultural perspectives of tribes on branding practice for sick children in Odisha, India.

Background & Objectives: Traditional beliefs on child healthcare at time lead to potentially harmful practices like branding. However, there is a gap in people's perceptions, attitudes and beliefs about branding practice. Therefore, the present study was undertaken to document the cultural motivation, ability and opportunity for branding practice in a tribal district of Odisha, India.

Stabilization of Eu in LiBO with the BO network through U co-doping and defect engineering.

Owing to the unique 4f-5d transitions and the involvement of 5d electrons, the divalent europium (Eu) ion is extensively used as a dopant ion in luminescent materials for phosphor-converted light emitting diodes (pc-LEDs) and other technological applications. Earlier reports in most of the cases have shown that the reduction of Eu to Eu requires very high temperatures and large hydrogen flux. In this study, a co-doping strategy with higher valent U ions was utilized to successfully stabilize Eu ions in the LiBO (LTB) host with both the BO and BO network in low H flux of only 8%.

Protective Effect of [Cu(NN)](ClO) Complex in Rainbow Trout Challenged against .

Previously, we reported an in vitro evaluation regarding antibacterial effects against by a new Cu (I) complex, [Cu(NN)](ClO). This study presents the results of an in vivo evaluation of [Cu(NN)](ClO) added as a dietary supplement against in rainbow trout. The results showed that the administration of [Cu(NN)](ClO) at 29 and 58 µg/g of fish for 15 days does not affect the growth of rainbow trout.

Tube length of chironomid larvae as an indicator for dissolved oxygen in water bodies.

Tube-building larvae of non-biting midges, or chironomids, are considered bioindicators of water pollution. The larvae use benthic particles to make their tubes and create a respiratory current with the movement of their bodies inside the tubes. The tube length of the chironomid larvae varies depending on several physicochemical properties of the aquatic medium.

Design of need-based phosphors and scintillators by compositional modulation in the ZnGaAlO:Cr spinel: pure compound solid solutions.

Materials that can depict persistent deep red light under both ultraviolet (UV) and X-ray illumination can be a boon to sustainable economy, particularly for optical imaging, solid state lighting, and anticounterfeiting applications. Herein, we have made a series of compounds starting from ZnGaO:Cr to ZnAlO:Cr (individual spinel) by substituting the varied concentration of Al in place of Ga in ZnGaAlO:Cr (solid solution). By virtue of the structural and defect engineering doping strategy, the photo and radioluminescence are expected to be improved.

Unraveling the site-specific energy transfer driven tunable emission characteristics of Eu & Tb co-doped Ca(PO)F phosphors.

In this study we have explored Ca(PO)F as host to develop a variety of phosphor materials with tunable emission and lifetime characteristics based on Eu and Tb as co-dopant ions and the energy transfer process involved with them. The energy transfer from the excited state of Tb ion to the D state of Eu makes it possible to tune the colour characteristics from yellow to orange to red. Further, such energy transfer process is highly dependent on the concentration of Eu and Tb ions and their site-selective distribution among the two different Ca-sites (CaO and CaOF) available.

Interim Analysis of Impact of Adding Low Dose Pulmonary Radiotherapy to Moderate COVID-19 Pneumonia Patients: IMpaCt-RT Study.

Background: Treatment for coronavirus disease 2019 (COVID-19) pneumonia remains largely supportive till date and multiple clinical trials took place within the short span of time to evaluate the role of investigational therapies. The anti-inflammatory effect of low dose whole lung radiation in treating pneumonia has been documented earlier. This clinical trial analyzed the effect of low dose radiation therapy (LDRT) in a moderately affected COVID-19 pneumonia patient cohort and has evaluated its effect in stopping the conversion of moderate disease into severe disease.

Harvesting Light from BaHfO/Eu through Ultraviolet, X-ray, and Heat Stimulation: An Optically Multifunctional Perovskite.

Materials with optical multifunctionality such as photoluminescence (PL), radioluminescence, and thermoluminescence (TL) are a boon for a sustainable society. BaHfO (barium hafnium oxide [BHO]) under UV irradiation demonstrated visible PL endowed by oxygen vacancies (OVs). Eu doping in BHO (BHOE) introduces f-state impurity levels just below the conduction band for both Eu@Ba and Eu@Hf sites, causing efficient host-to-dopant energy transfer, generating intense D → F magnetic dipole transitions (MDT) with internal quantum yield of ∼70%.

Mycobacterial Membranes as Actionable Targets for Lipid-Centric Therapy in Tuberculosis.

Infectious diseases remain significant health concerns worldwide, and resistance is particularly common in patients with tuberculosis caused by . The development of anti-infectives with novel modes of action may help overcome resistance. In this regard, membrane-active agents, which modulate membrane components essential for the survival of pathogens, present attractive antimicrobial agents.

Evaluation of the Antiviral Activity against Infectious Pancreatic Necrosis Virus (IPNV) of a Copper (I) Homoleptic Complex with a Coumarin as Ligand.

The aquatic infectious pancreatic necrosis virus (IPNV) causes a severe disease in farmed salmonid fish that generates great economic losses in the aquaculture industry. In the search for new tools to control the disease, in this paper we show the results obtained from the evaluation of the antiviral effect of [Cu(NN)](ClO) Cu(I) complex, synthesized in our laboratory, where the NN ligand is a synthetic derivate of the natural compound coumarin. This complex demonstrated antiviral activity against IPNV at 5.