A clinical evaluation of the effect of calf blood dialysate on the course of acute myocardial infarction.

The effect of daily intravenous treatment for 3 weeks with a calf blood dialysate presumed to improve disturbed oxidative metabolism was compared with placebo in a randomized double-blind study of 60 subjects with a first acute transmural myocardial infarction. Overall clinical evaluation of initial severity and clinical course suggested a better response of borderline significance in the dialysate-treated group. Blood enzyme elevations were statistically significantly less for that group on day 4 post-infarction for creatine kinase (CK) and aspartate aminotransferase (AspAT) but not for lactate dehydrogenase (LDH).

Efficacy of a single dose of slow-release isosorbide dinitrate in the treatment of silent or painful myocardial ischemia in stable angina pectoris.

A double-blind study was performed in 32 patients with stable angina pectoris to assess the effects of slow-release isosorbide dinitrate (ISDN) (a single dose of 120 mg/day) on the frequency and duration of painless and painful ischemic episodes, and on electrocardiographic changes and exercise tolerance. Forty-eight-hour electrocardiographic monitoring and treadmill exercise tests were performed before, and at 20 and 21 days of therapy. Holter monitoring showed a significant decrease in the frequency of painful and silent episodes (p less than 0.

[Arrhythmia and silent myocardial ischemia in patients after myocardial infarction].

In a group of 37 patients (30 men and 7 women aged from 36 to 67 years, men age 50.3) after a first acute myocardial infarction the frequency was analysed of the episodes of silent myocardial ischaemia with ST depression, and its correlation with arrhythmia was studied during outpatient ECG monitoring and exercise test on cycle ergometer. Outpatient ECG monitoring during 24 hours was done with a recorder Oxford Medilog MR-14 AM System 8-12 weeks after the onset of infarction.

[Evaluation of late surgical results in coronary disease supported by exercise stress test, noninvasive examination and work resumption].

The aim of the study was to assess effectiveness of surgery in management of coronary artery disease (CAD) during long-term follow-up in bearings of physical efficiency and work resumption. 21 males observed during 3-7 years after coronary artery by-pass grafting (CABG) underwent the study. Patients age ranged from 37 to 60 years (mean 51.

[Isosorbide dinitrate treatment of silent myocardial ischemia in patients after myocardial infarction].

In a group of 17 men and women aged 38-65 years (means = 51.1) three months after the first myocardial infarction we studied changes in silent ischemic ST segment depression by using Holter monitoring and exercise stress testing before and after 120 mg/daily of oral isosorbide dinitrate (Isoket). Repeated ECG monitoring and exercise stress test were performed after two weeks.

[Silent myocardial ischemia in patients after myocardial infarction].

Twenty-six men and women, aged 36-65 years, were studied 8-12 weeks after the first myocardial infarction with regard to silent ischemic ST-segment depression and heart rate by using 24-hour ambulatory electrocardiography and bicycle exercise testing. In 22 patients ambulatory ST-segment recordings revealed 81 episodes of ST-segment depression, including 34 (41.9%) painful and 47 (58.

Silent myocardial ischaemia in Holter monitoring and exercise stress testing after a first myocardial infarction.

Silent ischaemic ST segment depression and heart rate changes during ambulatory 24 h electrocardiography and bicycle exercise stress testing were studied 8-12 weeks after the first myocardial infarction in 22 patients, aged 36-65 years (X = 50.2). During Holter monitoring it was found that 18 patients had 64 episodes of ST segment depression, including 27 (42.