Synthesis, crystal structure and Hirshfeld surface analysis of -butyl -acetyl-carbamate.

This article reports a practical synthesis of -butyl acetyl-carbamate, CHNO, from -Boc-thio-acetamide and the study of its crystal structure. The reaction proceeds in the presence of natural phosphate as a catalyst, with excellent yield, simple workup and benign environment. The crystal structure was refined using a transferred multipolar atom model.