Publications by authors named "Moataz A ElKot"

Article Synopsis
  • Long-term diabetes can cause vascular problems, and this study explored how lncRNA LYPLAL1, miR-204-5p, and SIRT1 can serve as biomarkers for diagnosing diabetic microvascular complications (MVC).
  • Researchers found that lncRNA LYPLAL1 and SIRT1 levels were lower in patients with MVC, while miR-204-5p levels were higher compared to those without MVC.
  • The combination of these three markers showed 98.4% accuracy, with lncRNA LYPLAL1 being identified as a key independent predictor for MVC.
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Background: The triglyceride-glucose (TyG) index was shown to be an independent predictor of coronary artery disease (CAD) progression and prognosis. However, whether the TyG index can predict the severity of CAD in nondiabetic patients with chronic coronary syndrome remains unclear.

Methods: A total of 118 individuals who underwent elective coronary angiography were classified into group A (59 with coronary lesions) and group B (59 with normal coronary arteries; as a control group) after coronary angiography and laboratory tests for fasting and the postprandial (PP) TyG index.

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Hypertension is a serious medical condition that can increase the risk of developing heart, brain, kidney, and other diseases. Many asymptomatic hypertension patients experience asymptomatic organ damage (AOD). The purpose of this study was to determine the roles of LncRNA-GAS5 and β-catenin in predicting AOD in hypertensive nondiabetic patients.

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Background: For cardiologists, management of acute chest pain continues to be a challenge. Physicians struggle to avoid unnecessary admissions and at the same time not to miss high-risk patients needing urgent intervention. Therefore, diagnostic strategies focus on identifying patients in whom an acute coronary syndrome can be safely ruled out based on findings from history, physical examination, and early cardiac marker measurement.

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