Publications by authors named "Moatassem S Amer"
There is evidence consistent with the hypothesis that genetic, inflammatory and immune mechanisms are involved in the pathogenesis of AD. The aim of this study is to assess the relationship between Apolipoprotein E (Apo E), serum levels of inflammatory markers, and cognitive functions among elderly patients with Alzheimer's disease (AD) and Mild cognitive impairment (MCI) compared to elderly with normal cognitive function. 88 participants (≥60 years) from Ain Shams University Hospital were enrolled.
View Article and Find Full Text PDFPurpose: The underlying pathology for cognitive decline in diabetic patients is uncertain. It was originally linked to vascular causes; however, possible contribution of Alzheimer's pathology was debated. This study explored the link between salivary amyloid β42 level (as a surrogate marker for Alzheimer's pathology) and mild cognitive impairment (MCI) among old diabetic patients.
View Article and Find Full Text PDFUnlabelled: Framingham risk score (FRS) is a widely used tool to identify asymptomatic individuals who are at risk to cardiovascular disease. We aimed to investigate the association between subclinical atherosclerosis and FRS among elderly with both type 2 diabetes mellitus and healthy participants.
Methods: As case-control study was done on 58 men and women, who had type 2 diabetes mellitus, and in 59 age and gender matched control participants.
Quality of life in elderly diabetic patients with peripheral arterial disease.
Geriatr Gerontol Int
April 2013
Aim: To study the impact of peripheral arterial disease (PAD) on quality of life and functional status in Egyptian elderly diabetic patients.
Methods: This case-control study included 90 non-demented patients aged 60 years and older. Quality of life assessment was carried out using the Short Form 36 health survey (SF-36), Arterial duplex for diagnosis of peripheral arterial disease; Mini-Mental State Examination, Geriatric Depression Scale, Activity of Daily Living and Instrumental Activity of Daily Living were used.
Article Synopsis
- Hypertension is a key risk factor for atherosclerosis, and increased carotid artery intima-media thickness (IMT) serves as a noninvasive indicator of overall atherosclerotic disease.
- The study focused on older adults, examining 60 hypertensive individuals alongside 30 healthy controls, revealing that hypertensive patients had higher levels of body mass index, cholesterol, and inflammatory marker hs-CRP.
- Findings indicated that higher hs-CRP levels and longer hypertension duration correlated positively with increased carotid IMT, suggesting inflammation plays a more significant role in arterial thickening than other traditional risk factors.
Background: The pulmonary component of chronic obstructive pulmonary disease (COPD) is characterized by airflow limitation that is not fully reversible. The airflow limitation is usually progressive and associated with an abnormal inflammatory response of the lung to noxious particles or gases.
Hypothesis: The levels of the proinflammatory cytokines, interleukin 1 beta (IL-1β), tumor necrosis factor alfa (TNF-α), and C-reactive protein (CRP), in elderly patients suffering from COPD are increased.